Gene detail

G4418_RS05050

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_013299885

ClassHKTypeClassicLength583 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013299885#G4418_RS05050Stable P2CS identifier used across views.
GenomeGCF_013299885Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1149149Run 6 · 13 sequences · id 100% · cov 80% · representative
External referencesWP_173878776.1 · A0AAJ1EPH2 · MIST4 G4418_RS05050RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length583 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage252 / 583 aa (43.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa583 aa
HAMP: 288-357 aa (70 aa)1His_kinase: 372-452 aa (81 aa)2HATPase_c: 475-575 aa (101 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
288-357 aa · 70 aa · 12.0% of protein
Raw tokenHAMP:288:0.00000000217:357:70:69
2 His_kinase#2
372-452 aa · 81 aa · 13.9% of protein
Raw tokenHis_kinase:372:4.08e-22:452:81:80
3 HATPase_c#3
475-575 aa · 101 aa · 17.3% of protein
Raw tokenHATPase_c:475:0.000000000000112:575:105:109
  • Raw architecture: HAMP:288:0.00000000217:357:70:69#His_kinase:372:4.08e-22:452:81:80#HATPase_c:475:0.000000000000112:575:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013299885::NZ_JAAIMT010000007.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27883-30692Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4418_05050RefSeq proteinWP_173878776.1
Context group IDGCF_013299885::NZ_JAAIMT010000007.1::G00057
Context members
G4418_RS05045G4418_RS05050
Partner locus tags
G4418_RS05045G4418_RS05050
Partner old locus tags
G4418_05045G4418_05050
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_173878776.1Primary protein accession used for annex mappings.
UniProt accessionA0AAJ1EPH2Primary UniProt accession resolved in the annex database.
UniProt IDA0AAJ1EPH2_MEDGNDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4418_RS05050Primary locus identifier stored in the genes table.
Old locus tagG4418_05050Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIMT010000007.1Sequence record reported by the local genomic context database.
Genomic interval28 941-30 692 nt1 752 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 883-30 692 ntGCF_013299885::NZ_JAAIMT010000007.1::G00057

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013299885::NZ_JAAIMT010000007.1::G00057

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIMT010000007.1All displayed genes belong to this local TCS context.
Neighborhood span27 883-30 692 nt2 810 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 883 nt30 692 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4418_RS05045GCF_013299885#G4418_RS05045
RRunclassified

27 883-28 953 nt · Reverse (-)

Old locus G4418_05045RefSeq WP_039960197.1
G4418_RS05050GCF_013299885#G4418_RS05050
HKClassicCurrent focus

28 941-30 692 nt · Reverse (-)

Old locus G4418_05050RefSeq WP_173878776.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1149149Run 6 · HK · 13 sequences
Representative sequenceGCF_013299885#G4418_RS05050The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1149149

Simplified PFAM architecture for HKOC_1149149

PFAM domain coverage: 183 / 583 aa (31.4%)

1 aa583 aa
His_kinase: 372-451 aaHis_kinaseHATPase_c: 472-574 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[372-451] | HATPase_c[472-574]
  • Domain count: 2
  • Matched identifier: HKOC_1149149
  • Positioned domains: His_kinase 372-451 ; HATPase_c 472-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_013299885#G4418_RS05050

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_013299885
AssemblyASM1329988v1 · Contighaploid
Genome composition3 830 237 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 103 · HK 51 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key