Gene detail

G4465_RS02725

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_013299825

ClassHKTypeClassicLength522 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013299825#G4465_RS02725Stable P2CS identifier used across views.
GenomeGCF_013299825Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1385151Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_173863858.1 · MIST4 G4465_RS02725RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length522 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 522 aa (48.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa522 aa
HAMP: 230-298 aa (69 aa)1His_kinase: 315-393 aa (79 aa)2HATPase_c: 405-510 aa (106 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
230-298 aa · 69 aa · 13.2% of protein
Raw tokenHAMP:230:0.000000000000913:298:69:69
2 His_kinase#2
315-393 aa · 79 aa · 15.1% of protein
Raw tokenHis_kinase:315:3.36e-27:393:79:80
3 HATPase_c#3
405-510 aa · 106 aa · 20.3% of protein
Raw tokenHATPase_c:405:0.00000000000166:510:115:109
  • Raw architecture: HAMP:230:0.000000000000913:298:69:69#His_kinase:315:3.36e-27:393:79:80#HATPase_c:405:0.00000000000166:510:115:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013299825::NZ_JAAIMS010000003.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span92433-95710Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4465_02730RefSeq proteinWP_173863858.1
Context group IDGCF_013299825::NZ_JAAIMS010000003.1::G00028
Context members
G4465_RS02720G4465_RS02725
Partner locus tags
G4465_RS02720G4465_RS02725
Partner old locus tags
G4465_02725G4465_02730
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_173863858.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4465_RS02725Primary locus identifier stored in the genes table.
Old locus tagG4465_02730Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIMS010000003.1Sequence record reported by the local genomic context database.
Genomic interval94 142-95 710 nt1 569 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span92 433-95 710 ntGCF_013299825::NZ_JAAIMS010000003.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013299825::NZ_JAAIMS010000003.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIMS010000003.1All displayed genes belong to this local TCS context.
Neighborhood span92 433-95 710 nt3 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
92 433 nt95 710 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4465_RS02720GCF_013299825#G4465_RS02720
RRunclassified

92 433-93 986 nt · Forward (+)

Old locus G4465_02725RefSeq WP_173863857.1
G4465_RS02725GCF_013299825#G4465_RS02725
HKClassicCurrent focus

94 142-95 710 nt · Forward (+)

Old locus G4465_02730RefSeq WP_173863858.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1385151Run 6 · HK · 1 sequences
Representative sequenceGCF_013299825#G4465_RS02725The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1385151

Simplified PFAM architecture for HKOC_1385151

PFAM domain coverage: 231 / 522 aa (44.3%)

1 aa522 aa
HAMP: 248-298 aaHAMPHis_kinase: 315-390 aaHis_kinaseHATPase_c: 408-511 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[248-298] | His_kinase[315-390] | HATPase_c[408-511]
  • Domain count: 3
  • Matched identifier: HKOC_1385151
  • Positioned domains: HAMP 248-298 ; His_kinase 315-390 ; HATPase_c 408-511
Cluster members and taxonomy
Visualization

Representative gene: GCF_013299825#G4465_RS02725

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_013299825
AssemblyASM1329982v1 · Contighaploid
Genome composition3 191 344 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 83 · HK 40 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key