1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw token
HAMP:94:0.000000275:171:78:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HGQ81_RS00395
Histidine kinase, Classic
Clostridioides difficile · GCF_012955915
ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012955915#HGQ81_RS00395Stable P2CS identifier used across views.
GenomeGCF_012955915Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa407 aa
Domain-by-domain annotation3 items
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw token
HisKA:183:0.00000000308:248:66:643 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw token
HATPase_c:298:3.83e-26:404:107:109- Raw architecture: HAMP:94:0.000000275:171:78:69#HisKA:183:0.00000000308:248:66:64#HATPase_c:298:3.83e-26:404:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_012955915::NZ_JABBZF010000001.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87621-89756Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHGQ81_00395RefSeq proteinWP_330396909.1
Context group ID
GCF_012955915::NZ_JABBZF010000001.1::G00012Context members
HGQ81_RS00390HGQ81_RS00395
Partner locus tags
HGQ81_RS00390HGQ81_RS00395
Partner old locus tags
HGQ81_00390HGQ81_00395
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_330396909.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHGQ81_RS00395Primary locus identifier stored in the genes table.
Old locus tagHGQ81_00395Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JABBZF010000001.1Sequence record reported by the local genomic context database.
Genomic interval88 533-89 756 nt1 224 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87 621-89 756 ntGCF_012955915::NZ_JABBZF010000001.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_012955915::NZ_JABBZF010000001.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JABBZF010000001.1All displayed genes belong to this local TCS context.
Neighborhood span87 621-89 756 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 621 nt89 756 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HGQ81_RS00390GCF_012955915#HGQ81_RS00390
RROmpR
87 621-88 313 nt · Forward (+)
HGQ81_RS00395GCF_012955915#HGQ81_RS00395
HKClassicCurrent focus
88 533-89 756 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002165155#DCQ05_RS07865Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2381022
Simplified PFAM architecture for HKOC_2381022
PFAM domain coverage: 172 / 407 aa (42.3%)
1 aa407 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[184-248] | HATPase_c[298-404]
- Domain count: 2
- Matched identifier: HKOC_2381022
- Positioned domains: HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Representative gene: GCF_002165155#DCQ05_RS07865
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_012955915
AssemblyASM1295591v1 · Contighaploid
Genome composition4 069 250 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key