Gene detail

HGQ81_RS00280

Response regulator, RpfG family

Clostridioides difficile · GCF_012955915

ClassRRTypeRpfGLength546 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012955915#HGQ81_RS00280Stable P2CS identifier used across views.
GenomeGCF_012955915Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0079329Run 7 · 118 sequences · id 100% · cov 80%
External referencesWP_009901919.1 · A0AB74QCM1 · MIST4 HGQ81_RS00280RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHDGGDEF
Protein length546 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage356 / 546 aa (65.2%)Merged over positioned domains only.
Domain description1 Response_reg,1 HD,1 GGDEFSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa546 aa
Response_reg: 6-110 aa (105 aa)1HD: 195-300 aa (106 aa)2GGDEF: 384-528 aa (145 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
6-110 aa · 105 aa · 19.2% of protein
Raw tokenResponse_reg:6:5.98e-27:110:106:111
2 HD#2
195-300 aa · 106 aa · 19.4% of protein
Raw tokenHD:195:0.00000000000785:300:106:110
3 GGDEF#3
384-528 aa · 145 aa · 26.6% of protein
Raw tokenGGDEF:384:3.37e-40:528:162:160
  • Raw architecture: Response_reg:6:5.98e-27:110:106:111#HD:195:0.00000000000785:300:106:110#GGDEF:384:3.37e-40:528:162:160
  • Domain description: 1 Response_reg,1 HD,1 GGDEF
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012955915::NZ_JABBZF010000001.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span60967-65535Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHGQ81_00280RefSeq proteinWP_009901919.1
Context group IDGCF_012955915::NZ_JABBZF010000001.1::G00010
Context members
HGQ81_RS00270HGQ81_RS00280
Partner locus tags
HGQ81_RS00270HGQ81_RS00280
Partner old locus tags
HGQ81_00270HGQ81_00280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009901919.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QCM1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QCM1_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHGQ81_RS00280Primary locus identifier stored in the genes table.
Old locus tagHGQ81_00280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JABBZF010000001.1Sequence record reported by the local genomic context database.
Genomic interval63 895-65 535 nt1 641 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span60 967-65 535 ntGCF_012955915::NZ_JABBZF010000001.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012955915::NZ_JABBZF010000001.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JABBZF010000001.1All displayed genes belong to this local TCS context.
Neighborhood span60 967-65 535 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 967 nt65 535 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HGQ81_RS00270GCF_012955915#HGQ81_RS00270
HKHybrid

60 967-63 525 nt · Reverse (-)

Old locus HGQ81_00270RefSeq WP_167653827.1
HGQ81_RS00280GCF_012955915#HGQ81_RS00280
RRRpfGCurrent focus

63 895-65 535 nt · Reverse (-)

Old locus HGQ81_00280RefSeq WP_009901919.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0079329Run 7 · RR · 118 sequences
Representative sequenceGCF_000155025#UAB_RS0203460Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HD_5 + GGDEF3 domains in the representative PFAM annotation.

PFAM architecture for RROC_0079329

Simplified PFAM architecture for RROC_0079329

PFAM domain coverage: 385 / 546 aa (70.5%)

1 aa546 aa
Response_reg: 6-117 aaResponse_regResponse_reg: 6-117 aaResponse_regHD_5: 191-320 aaHD_5HD_5: 191-320 aaHD_5GGDEF: 384-526 aaGGDEFGGDEF: 384-526 aaGGDEF
Response_regHD_5GGDEF
  • Simplified architecture: Response_reg + HD_5 + GGDEF
  • Raw architecture: Response_reg[6-117] | HD_5[191-320] | GGDEF[384-526]
  • Domain count: 3
  • Matched identifier: RROC_0079329
  • Positioned domains: Response_reg 6-117 ; Response_reg 6-117 ; HD_5 191-320 ; HD_5 191-320 ; GGDEF 384-526 ; GGDEF 384-526
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203460

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012955915
AssemblyASM1295591v1 · Contighaploid
Genome composition4 069 250 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key