1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw token
HisKA:117:0.000000000309:177:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HCN89_RS18815
Histidine kinase, Classic
Clostridioides difficile · GCF_012952655
ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012952655#HCN89_RS18815Stable P2CS identifier used across views.
GenomeGCF_012952655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw token
HATPase_c:222:2.12e-24:328:108:109- Raw architecture: HisKA:117:0.000000000309:177:61:64#HATPase_c:222:2.12e-24:328:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_012952655::NZ_JAATIE010000001.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4062953-4064615Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHCN89_18815RefSeq proteinWP_003422275.1
Context group ID
GCF_012952655::NZ_JAATIE010000001.1::G00052Context members
HCN89_RS18815HCN89_RS18820
Partner locus tags
HCN89_RS18815HCN89_RS18820
Partner old locus tags
HCN89_18815HCN89_18820
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003422275.1Primary protein accession used for annex mappings.
UniProt accessionD5Q9Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q9Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHCN89_RS18815Primary locus identifier stored in the genes table.
Old locus tagHCN89_18815Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAATIE010000001.1Sequence record reported by the local genomic context database.
Genomic interval4 062 953-4 063 942 nt990 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 062 953-4 064 615 ntGCF_012952655::NZ_JAATIE010000001.1::G00052
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_012952655::NZ_JAATIE010000001.1::G00052Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAATIE010000001.1All displayed genes belong to this local TCS context.
Neighborhood span4 062 953-4 064 615 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 062 953 nt4 064 615 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HCN89_RS18815GCF_012952655#HCN89_RS18815
HKClassicCurrent focus
4 062 953-4 063 942 nt · Reverse (-)
HCN89_RS18820GCF_012952655#HCN89_RS18820
RROmpR
4 063 929-4 064 615 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0217625Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2857951
Simplified PFAM architecture for HKOC_2857951
PFAM domain coverage: 169 / 329 aa (51.4%)
1 aa329 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[116-177] | HATPase_c[222-328]
- Domain count: 2
- Matched identifier: HKOC_2857951
- Positioned domains: HisKA 116-177 ; HATPase_c 222-328
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0217625
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_012952655
AssemblyASM1295265v1 · Contighaploid
Genome composition4 226 733 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 48 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key