Gene detail

HCN89_RS02660

Histidine kinase, Classic

Clostridioides difficile · GCF_012952655

ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012952655#HCN89_RS02660Stable P2CS identifier used across views.
GenomeGCF_012952655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1783726Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_003417837.1 · D5Q0A2 · MIST4 HCN89_RS02660RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HCN89_RS02660
Domain-by-domain annotation3 items
1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw tokenHAMP:170:0.00000000000625:237:68:69
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw tokenHisKA:249:0.000000000254:308:61:64
3 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw tokenHATPase_c:355:0.00000000000000176:439:88:109
  • Raw architecture: HAMP:170:0.00000000000625:237:68:69#HisKA:249:0.000000000254:308:61:64#HATPase_c:355:0.00000000000000176:439:88:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012952655::NZ_JAATIE010000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span500541-502575Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHCN89_02660RefSeq proteinWP_003417837.1
Context group IDGCF_012952655::NZ_JAATIE010000001.1::G00005
Context members
HCN89_RS02655HCN89_RS02660
Partner locus tags
HCN89_RS02655HCN89_RS02660
Partner old locus tags
HCN89_02655HCN89_02660
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417837.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0A2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0A2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHCN89_RS02660Primary locus identifier stored in the genes table.
Old locus tagHCN89_02660Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAATIE010000001.1Sequence record reported by the local genomic context database.
Genomic interval501 181-502 575 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span500 541-502 575 ntGCF_012952655::NZ_JAATIE010000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012952655::NZ_JAATIE010000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAATIE010000001.1All displayed genes belong to this local TCS context.
Neighborhood span500 541-502 575 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
500 541 nt502 575 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HCN89_RS02655GCF_012952655#HCN89_RS02655
RROmpR

500 541-501 188 nt · Forward (+)

Old locus HCN89_02655RefSeq WP_003417836.1
HCN89_RS02660GCF_012952655#HCN89_RS02660
HKClassicCurrent focus

501 181-502 575 nt · Forward (+)

Old locus HCN89_02660RefSeq WP_003417837.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1783726Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1783726

Simplified PFAM architecture for HKOC_1783726

PFAM domain coverage: 195 / 464 aa (42.0%)

1 aa464 aa
HAMP: 187-236 aaHAMPHisKA: 250-308 aaHisKAHATPase_c: 355-440 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
  • Domain count: 3
  • Matched identifier: HKOC_1783726
  • Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012952655
AssemblyASM1295265v1 · Contighaploid
Genome composition4 226 733 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 48 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key