Gene detail

HCN89_RS00365

Response regulator OmpR family

Clostridioides difficile · GCF_012952655

ClassRRTypeOmpRLength244 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012952655#HCN89_RS00365Stable P2CS identifier used across views.
GenomeGCF_012952655Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0806097Run 7 · 300 sequences · id 100% · cov 80%
External referencesWP_003421230.1 · D5Q1S1 · MIST4 HCN89_RS00365RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length244 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage188 / 244 aa (77.0%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HCN89_RS00365
Domain-by-domain annotation2 items
1 Response_reg#1
11-121 aa · 111 aa · 45.5% of protein
Raw tokenResponse_reg:11:2.99e-30:121:112:111
2 Trans_reg_C#2
162-238 aa · 77 aa · 31.6% of protein
Raw tokenTrans_reg_C:162:2.2e-28:238:77:77
  • Raw architecture: Response_reg:11:2.99e-30:121:112:111#Trans_reg_C:162:2.2e-28:238:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012952655::NZ_JAATIE010000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41454-43290Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHCN89_00365RefSeq proteinWP_003421230.1
Context group IDGCF_012952655::NZ_JAATIE010000001.1::G00001
Context members
HCN89_RS19780HCN89_RS00365
Partner locus tags
HCN89_RS19780HCN89_RS00365
Partner old locus tags
HCN89_00365
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003421230.1Primary protein accession used for annex mappings.
UniProt accessionD5Q1S1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q1S1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHCN89_RS00365Primary locus identifier stored in the genes table.
Old locus tagHCN89_00365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAATIE010000001.1Sequence record reported by the local genomic context database.
Genomic interval42 556-43 290 nt735 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span41 454-43 290 ntGCF_012952655::NZ_JAATIE010000001.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012952655::NZ_JAATIE010000001.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAATIE010000001.1All displayed genes belong to this local TCS context.
Neighborhood span41 454-43 290 nt1 837 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 454 nt43 290 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HCN89_RS19780GCF_012952655#HCN89_RS19780
HKClassic

41 454-42 218 nt · Reverse (-)

RefSeq WP_223380601.1
HCN89_RS00365GCF_012952655#HCN89_RS00365
RROmpRCurrent focus

42 556-43 290 nt · Reverse (-)

Old locus HCN89_00365RefSeq WP_003421230.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0806097Run 7 · RR · 300 sequences
Representative sequenceGCF_000155065#QAE_RS0200315Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_0806097

Simplified PFAM architecture for RROC_0806097

PFAM domain coverage: 188 / 244 aa (77.0%)

1 aa244 aa
Response_reg: 11-121 aaResponse_regResponse_reg: 11-121 aaResponse_regTrans_reg_C: 162-238 aaTrans_reg_CTrans_reg_C: 162-238 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[11-121] | Trans_reg_C[162-238]
  • Domain count: 2
  • Matched identifier: RROC_0806097
  • Positioned domains: Response_reg 11-121 ; Response_reg 11-121 ; Trans_reg_C 162-238 ; Trans_reg_C 162-238
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0200315

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012952655
AssemblyASM1295265v1 · Contighaploid
Genome composition4 226 733 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 48 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key