Gene detail

GSQ50_RS12985

Histidine kinase, Classic

Clostridioides difficile · GCF_012276945

ClassHKTypeClassicLength389 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012276945#GSQ50_RS12985Stable P2CS identifier used across views.
GenomeGCF_012276945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1676206Run 6 · 20 sequences · id 100% · cov 80%
External referencesWP_330405476.1 · MIST4 GSQ50_RS12985RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length389 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 389 aa (64.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa389 aa
HAMP: 76-153 aa (78 aa)1HisKA: 165-230 aa (66 aa)2HATPase_c: 280-386 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
76-153 aa · 78 aa · 20.1% of protein
Raw tokenHAMP:76:0.00000000759:153:78:69
2 HisKA#2
165-230 aa · 66 aa · 17.0% of protein
Raw tokenHisKA:165:0.00000000118:230:66:64
3 HATPase_c#3
280-386 aa · 107 aa · 27.5% of protein
Raw tokenHATPase_c:280:1e-26:386:107:109
  • Raw architecture: HAMP:76:0.00000000759:153:78:69#HisKA:165:0.00000000118:230:66:64#HATPase_c:280:1e-26:386:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012276945::NZ_JAAXLR010000035.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17951-20086Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ50_12985RefSeq proteinWP_330405476.1
Context group IDGCF_012276945::NZ_JAAXLR010000035.1::G00026
Context members
GSQ50_RS12980GSQ50_RS12985
Partner locus tags
GSQ50_RS12980GSQ50_RS12985
Partner old locus tags
GSQ50_12980GSQ50_12985
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330405476.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ50_RS12985Primary locus identifier stored in the genes table.
Old locus tagGSQ50_12985Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAXLR010000035.1Sequence record reported by the local genomic context database.
Genomic interval18 917-20 086 nt1 170 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 951-20 086 ntGCF_012276945::NZ_JAAXLR010000035.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012276945::NZ_JAAXLR010000035.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAXLR010000035.1All displayed genes belong to this local TCS context.
Neighborhood span17 951-20 086 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 951 nt20 086 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ50_RS12980GCF_012276945#GSQ50_RS12980
RROmpR

17 951-18 643 nt · Forward (+)

Old locus GSQ50_12980RefSeq WP_167650414.1
GSQ50_RS12985GCF_012276945#GSQ50_RS12985
HKClassicCurrent focus

18 917-20 086 nt · Forward (+)

Old locus GSQ50_12985RefSeq WP_330405476.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1676206Run 6 · HK · 20 sequences
Representative sequenceGCF_001971865#BER27_RS02755Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1676206

Simplified PFAM architecture for HKOC_1676206

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1676206
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_001971865#BER27_RS02755

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012276945
AssemblyASM1227694v1 · Contighaploid
Genome composition4 120 378 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key