Gene detail

GSQ50_RS01235

Histidine kinase, Classic

Clostridioides difficile · GCF_012276945

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012276945#GSQ50_RS01235Stable P2CS identifier used across views.
GenomeGCF_012276945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2114724Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_168346869.1 · MIST4 GSQ50_RS01235RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
HisKA: 218-278 aa (61 aa)1HATPase_c: 334-433 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.000000000065:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:1.57e-24:433:100:109
  • Raw architecture: HisKA:218:0.000000000065:278:61:64#HATPase_c:334:1.57e-24:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012276945::NZ_JAAXLR010000002.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18991-21002Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ50_01235RefSeq proteinWP_168346869.1
Context group IDGCF_012276945::NZ_JAAXLR010000002.1::G00018
Context members
GSQ50_RS01235GSQ50_RS01240
Partner locus tags
GSQ50_RS01235GSQ50_RS01240
Partner old locus tags
GSQ50_01235GSQ50_01240
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_168346869.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ50_RS01235Primary locus identifier stored in the genes table.
Old locus tagGSQ50_01235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAXLR010000002.1Sequence record reported by the local genomic context database.
Genomic interval18 991-20 301 nt1 311 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span18 991-21 002 ntGCF_012276945::NZ_JAAXLR010000002.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012276945::NZ_JAAXLR010000002.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAXLR010000002.1All displayed genes belong to this local TCS context.
Neighborhood span18 991-21 002 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 991 nt21 002 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ50_RS01235GCF_012276945#GSQ50_RS01235
HKClassicCurrent focus

18 991-20 301 nt · Reverse (-)

Old locus GSQ50_01235RefSeq WP_168346869.1
GSQ50_RS01240GCF_012276945#GSQ50_RS01240
RROmpR

20 295-21 002 nt · Reverse (-)

Old locus GSQ50_01240RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2114724Run 6 · HK · 7 sequences
Representative sequenceGCF_002891605#AMR89_RS00645Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2114724

Simplified PFAM architecture for HKOC_2114724

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2114724
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891605#AMR89_RS00645

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012276945
AssemblyASM1227694v1 · Contighaploid
Genome composition4 120 378 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key