Gene detail

GSQ50_RS02505

Histidine kinase, Classic

Clostridioides difficile · GCF_012276945

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012276945#GSQ50_RS02505Stable P2CS identifier used across views.
GenomeGCF_012276945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1729061Run 6 · 8 sequences · id 100% · cov 80%
External referencesWP_102814615.1 · MIST4 GSQ50_RS02505RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
H_kinase_N: 12-142 aa (131 aa)1HisKA_2: 276-350 aa (75 aa)2HATPase_c: 370-467 aa (98 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.33e-35:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.53e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.000000103:467:114:109
  • Raw architecture: H_kinase_N:12:1.33e-35:142:132:139#HisKA_2:276:2.53e-16:350:76:76#HATPase_c:370:0.000000103:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012276945::NZ_JAAXLR010000004.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2734-4711Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ50_02505RefSeq proteinWP_102814615.1
Context group IDGCF_012276945::NZ_JAAXLR010000004.1::G00036
Context members
GSQ50_RS02500GSQ50_RS02505
Partner locus tags
GSQ50_RS02500GSQ50_RS02505
Partner old locus tags
GSQ50_02500GSQ50_02505
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_102814615.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ50_RS02505Primary locus identifier stored in the genes table.
Old locus tagGSQ50_02505Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAXLR010000004.1Sequence record reported by the local genomic context database.
Genomic interval3 302-4 711 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 734-4 711 ntGCF_012276945::NZ_JAAXLR010000004.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012276945::NZ_JAAXLR010000004.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAXLR010000004.1All displayed genes belong to this local TCS context.
Neighborhood span2 734-4 711 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 734 nt4 711 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ50_RS02500GCF_012276945#GSQ50_RS02500
RRAmiR_NasR

2 734-3 309 nt · Forward (+)

Old locus GSQ50_02500RefSeq WP_003423977.1
GSQ50_RS02505GCF_012276945#GSQ50_RS02505
HKClassicCurrent focus

3 302-4 711 nt · Forward (+)

Old locus GSQ50_02505RefSeq WP_102814615.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1729061Run 6 · HK · 8 sequences
Representative sequenceGCF_002891605#AMR89_RS05945Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1729061

Simplified PFAM architecture for HKOC_1729061

PFAM domain coverage: 302 / 469 aa (64.4%)

1 aa469 aa
GAF_PdtaS: 6-141 aaGAF_PdtaSHisKA_2: 276-347 aaHisKA_2HATPase_c: 373-466 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
  • Domain count: 3
  • Matched identifier: HKOC_1729061
  • Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_002891605#AMR89_RS05945

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 8 over 8 total members. Page 1 / 1.

GCF_002891605#AMR89_RS05945 (representative)
AMR89_RS05945 · HK · Classic
RefSeq: WP_102814615.1
GCF_012276945#GSQ50_RS02505
GSQ50_RS02505 · HK · Classic
RefSeq: WP_102814615.1
GCF_023656865#NBN67_RS09310
NBN67_RS09310 · HK · Classic
RefSeq: WP_102814615.1
GCF_023656875#NB460_RS09690
NB460_RS09690 · HK · Classic
RefSeq: WP_102814615.1
GCF_023656905#NB459_RS09695
NB459_RS09695 · HK · Classic
RefSeq: WP_102814615.1
GCF_024260125#NMF90_RS10910
NMF90_RS10910 · HK · Classic
RefSeq: WP_102814615.1
GCF_024260155#NMF83_RS04430
NMF83_RS04430 · HK · Classic
RefSeq: WP_102814615.1
GCF_024260185#NMF94_RS08780
NMF94_RS08780 · HK · Classic
RefSeq: WP_102814615.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012276945
AssemblyASM1227694v1 · Contighaploid
Genome composition4 120 378 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 48 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key