Gene detail

GSQ43_RS00495

Histidine kinase, Classic

Clostridioides difficile · GCF_012030175

ClassHKTypeClassicLength309 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_012030175#GSQ43_RS00495Stable P2CS identifier used across views.
GenomeGCF_012030175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1356534Run 6 · 14 sequences · id 100% · cov 80%
External referencesWP_167654309.1 · MIST4 GSQ43_RS00495RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length309 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 309 aa (49.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for GSQ43_RS00495
Domain-by-domain annotation2 items
1 HisKA#1
88-154 aa · 67 aa · 21.7% of protein
Raw tokenHisKA:88:0.0000000000000565:154:67:64
2 HATPase_c#2
207-292 aa · 86 aa · 27.8% of protein
Raw tokenHATPase_c:207:0.0000000719:292:90:109
  • Raw architecture: HisKA:88:0.0000000000000565:154:67:64#HATPase_c:207:0.0000000719:292:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_012030175::NZ_JAAUXG010000002.1::G00030
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-931Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ43_00490RefSeq proteinWP_167654309.1
Context group IDGCF_012030175::NZ_JAAUXG010000002.1::G00030
Context members
GSQ43_RS00495
Partner locus tags
GSQ43_RS00495
Partner old locus tags
GSQ43_00490
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_167654309.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ43_RS00495Primary locus identifier stored in the genes table.
Old locus tagGSQ43_00490Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAUXG010000002.1Sequence record reported by the local genomic context database.
Genomic interval1-931 nt931 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-931 ntGCF_012030175::NZ_JAAUXG010000002.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012030175::NZ_JAAUXG010000002.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAUXG010000002.1All displayed genes belong to this local TCS context.
Neighborhood span1-931 nt931 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt931 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1356534Run 6 · HK · 14 sequences
Representative sequenceGCF_003456975#CDIF102859_RS12950Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1356534

Simplified PFAM architecture for HKOC_1356534

PFAM domain coverage: 190 / 530 aa (35.8%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-509 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-509]
  • Domain count: 3
  • Matched identifier: HKOC_1356534
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-509
Cluster members and taxonomy
Visualization

Representative gene: GCF_003456975#CDIF102859_RS12950

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012030175
AssemblyASM1203017v1 · Contighaploid
Genome composition4 172 576 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key