Gene detail

BXA52_RS13740

Histidine kinase, Classic

Enterococcus faecium · GCF_011316265

ClassHKTypeClassicLength513 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_011316265#BXA52_RS13740Stable P2CS identifier used across views.
GenomeGCF_011316265Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1416543Run 6 · 2523 sequences · id 100% · cov 80% · representative
External referencesWP_165636624.1 · MIST4 BXA52_RS13740RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length513 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 513 aa (48.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for BXA52_RS13740
Domain-by-domain annotation3 items
1 HAMP#1
198-268 aa · 71 aa · 13.8% of protein
Raw tokenHAMP:198:0.000000000000435:268:71:69
2 HisKA#2
273-339 aa · 67 aa · 13.1% of protein
Raw tokenHisKA:273:0.00000000000000274:339:67:64
3 HATPase_c#3
387-497 aa · 111 aa · 21.6% of protein
Raw tokenHATPase_c:387:9.39e-28:497:111:109
  • Raw architecture: HAMP:198:0.000000000000435:268:71:69#HisKA:273:0.00000000000000274:339:67:64#HATPase_c:387:9.39e-28:497:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_011316265::NZ_MTRX01000289.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1723-3947Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBXA52_14850RefSeq proteinWP_165636624.1
Context group IDGCF_011316265::NZ_MTRX01000289.1::G00014
Context members
BXA52_RS13735BXA52_RS13740
Partner locus tags
BXA52_RS13735BXA52_RS13740
Partner old locus tags
BXA52_14845BXA52_14850
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_165636624.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBXA52_RS13740Primary locus identifier stored in the genes table.
Old locus tagBXA52_14850Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTRX01000289.1Sequence record reported by the local genomic context database.
Genomic interval2 406-3 947 nt1 542 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 723-3 947 ntGCF_011316265::NZ_MTRX01000289.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_011316265::NZ_MTRX01000289.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTRX01000289.1All displayed genes belong to this local TCS context.
Neighborhood span1 723-3 947 nt2 225 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 723 nt3 947 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BXA52_RS13735GCF_011316265#BXA52_RS13735
RROmpR

1 723-2 409 nt · Forward (+)

Old locus BXA52_14845RefSeq WP_002290973.1
BXA52_RS13740GCF_011316265#BXA52_RS13740
HKClassicCurrent focus

2 406-3 947 nt · Forward (+)

Old locus BXA52_14850RefSeq WP_165636624.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1416543Run 6 · HK · 2523 sequences
Representative sequenceGCF_011316265#BXA52_RS13740The current gene is the representative for this cluster.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1416543

Simplified PFAM architecture for HKOC_1416543

PFAM domain coverage: 377 / 513 aa (73.5%)

1 aa513 aa
ArlS_N: 46-193 aaArlS_NHAMP: 215-268 aaHAMPHisKA: 274-339 aaHisKAHATPase_c: 388-496 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[46-193] | HAMP[215-268] | HisKA[274-339] | HATPase_c[388-496]
  • Domain count: 4
  • Matched identifier: HKOC_1416543
  • Positioned domains: ArlS_N 46-193 ; HAMP 215-268 ; HisKA 274-339 ; HATPase_c 388-496
Cluster members and taxonomy
Visualization

Representative gene: GCF_011316265#BXA52_RS13740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_011316265
AssemblyASM1131626v1 · Contighaploid
Genome composition3 470 500 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 40 · HK 18 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key