Gene detail

BXA52_RS04945

Histidine kinase, Classic

Enterococcus faecium · GCF_011316265

ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_011316265#BXA52_RS04945Stable P2CS identifier used across views.
GenomeGCF_011316265Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1549839Run 6 · 2832 sequences · id 100% · cov 80%
External referencesWP_002288588.1 · Q3XZ23 · MIST4 BXA52_RS04945RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 482 aa (50.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
HAMP: 179-244 aa (66 aa)1HisKA: 255-321 aa (67 aa)2HATPase_c: 366-475 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
179-244 aa · 66 aa · 13.7% of protein
Raw tokenHAMP:179:0.000000000000447:244:66:69
2 HisKA#2
255-321 aa · 67 aa · 13.9% of protein
Raw tokenHisKA:255:0.00000000000000146:321:67:64
3 HATPase_c#3
366-475 aa · 110 aa · 22.8% of protein
Raw tokenHATPase_c:366:6.3e-31:475:110:109
  • Raw architecture: HAMP:179:0.000000000000447:244:66:69#HisKA:255:0.00000000000000146:321:67:64#HATPase_c:366:6.3e-31:475:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_011316265::NZ_MTRX01000082.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2476-4640Genomic interval covered by the local TCS group.
Identifiers
Old locus tagBXA52_05255RefSeq proteinWP_002288588.1
Context group IDGCF_011316265::NZ_MTRX01000082.1::G00023
Context members
BXA52_RS04940BXA52_RS04945
Partner locus tags
BXA52_RS04940BXA52_RS04945
Partner old locus tags
BXA52_05250BXA52_05255
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002288588.1Primary protein accession used for annex mappings.
UniProt accessionQ3XZ23Primary UniProt accession resolved in the annex database.
UniProt IDQ3XZ23_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagBXA52_RS04945Primary locus identifier stored in the genes table.
Old locus tagBXA52_05255Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_MTRX01000082.1Sequence record reported by the local genomic context database.
Genomic interval3 192-4 640 nt1 449 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 476-4 640 ntGCF_011316265::NZ_MTRX01000082.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_011316265::NZ_MTRX01000082.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_MTRX01000082.1All displayed genes belong to this local TCS context.
Neighborhood span2 476-4 640 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 476 nt4 640 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

BXA52_RS04940GCF_011316265#BXA52_RS04940
RROmpR

2 476-3 192 nt · Forward (+)

Old locus BXA52_05250RefSeq WP_002288590.1
BXA52_RS04945GCF_011316265#BXA52_RS04945
HKClassicCurrent focus

3 192-4 640 nt · Forward (+)

Old locus BXA52_05255RefSeq WP_002288588.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1549839Run 6 · HK · 2832 sequences
Representative sequenceGCF_000157435#EFPG_RS03405Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1549839

Simplified PFAM architecture for HKOC_1549839

PFAM domain coverage: 225 / 488 aa (46.1%)

1 aa488 aa
HAMP: 194-243 aaHAMPHisKA: 256-320 aaHisKAHATPase_c: 367-476 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[194-243] | HisKA[256-320] | HATPase_c[367-476]
  • Domain count: 3
  • Matched identifier: HKOC_1549839
  • Positioned domains: HAMP 194-243 ; HisKA 256-320 ; HATPase_c 367-476
Cluster members and taxonomy
Visualization

Representative gene: GCF_000157435#EFPG_RS03405

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 352 · GCF_011316265
AssemblyASM1131626v1 · Contighaploid
Genome composition3 470 500 bp · 38,0% GCEnterococcus faecium
Signal transduction countsGenes 40 · HK 18 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key