Gene detail

GT593_RS02635

Histidine kinase, Classic

Dorea longicatena · GCF_009875695

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009875695#GT593_RS02635Stable P2CS identifier used across views.
GenomeGCF_009875695Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_2558300Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_022416139.1 · A0A173TSY9 · MIST4 GT593_RS02635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 386 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 89-159 aa (71 aa)1HisKA: 164-230 aa (67 aa)2HATPase_c: 272-381 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
89-159 aa · 71 aa · 18.4% of protein
Raw tokenHAMP:89:0.0000000000411:159:71:69
2 HisKA#2
164-230 aa · 67 aa · 17.4% of protein
Raw tokenHisKA:164:0.000000000117:230:67:64
3 HATPase_c#3
272-381 aa · 110 aa · 28.5% of protein
Raw tokenHATPase_c:272:4.04e-32:381:110:109
  • Raw architecture: HAMP:89:0.0000000000411:159:71:69#HisKA:164:0.000000000117:230:67:64#HATPase_c:272:4.04e-32:381:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_009875695::NZ_WWSD01000002.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span259039-260882Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGT593_02645RefSeq proteinWP_022416139.1
Context group IDGCF_009875695::NZ_WWSD01000002.1::G00033
Context members
GT593_RS02630GT593_RS02635
Partner locus tags
GT593_RS02630GT593_RS02635
Partner old locus tags
GT593_02640GT593_02645
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022416139.1Primary protein accession used for annex mappings.
UniProt accessionA0A173TSY9Primary UniProt accession resolved in the annex database.
UniProt IDA0A173TSY9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 2Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGT593_RS02635Primary locus identifier stored in the genes table.
Old locus tagGT593_02645Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_WWSD01000002.1Sequence record reported by the local genomic context database.
Genomic interval259 722-260 882 nt1 161 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span259 039-260 882 ntGCF_009875695::NZ_WWSD01000002.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_009875695::NZ_WWSD01000002.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_WWSD01000002.1All displayed genes belong to this local TCS context.
Neighborhood span259 039-260 882 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
259 039 nt260 882 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GT593_RS02630GCF_009875695#GT593_RS02630
RROmpR

259 039-259 722 nt · Forward (+)

Old locus GT593_02640RefSeq WP_006426539.1
GT593_RS02635GCF_009875695#GT593_RS02635
HKClassicCurrent focus

259 722-260 882 nt · Forward (+)

Old locus GT593_02645RefSeq WP_022416139.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2558300Run 6 · HK · 39 sequences
Representative sequenceGCF_001404635#AQ990_RS03350Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2558300

Simplified PFAM architecture for HKOC_2558300

PFAM domain coverage: 174 / 386 aa (45.1%)

1 aa386 aa
HisKA: 164-229 aaHisKAHATPase_c: 275-382 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[164-229] | HATPase_c[275-382]
  • Domain count: 2
  • Matched identifier: HKOC_2558300
  • Positioned domains: HisKA 164-229 ; HATPase_c 275-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_001404635#AQ990_RS03350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 88 431 · GCF_009875695
AssemblyASM987569v1 · Scaffoldhaploid
Genome composition3 122 554 bp · 41,5% GCDorea longicatena
Signal transduction countsGenes 78 · HK 37 · RR 40CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key