Gene detail

GMD29_RS10960

Histidine kinase, Classic

Roseburia faecis · GCF_009718405

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009718405#GMD29_RS10960Stable P2CS identifier used across views.
GenomeGCF_009718405Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1048005Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_082413759.1 · A0A0M6WHJ5 · MIST4 GMD29_RS10960RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage446 / 601 aa (74.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 82-278 aa (197 aa)1HAMP: 297-358 aa (62 aa)2His_kinase: 380-459 aa (80 aa)3HATPase_c: 475-581 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
82-278 aa · 197 aa · 32.8% of protein
Raw tokendCache_1:82:0.00000000281:278:206:195
2 HAMP#2
297-358 aa · 62 aa · 10.3% of protein
Raw tokenHAMP:297:0.0000579:358:62:69
3 His_kinase#3
380-459 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:380:6.57e-34:459:80:80
4 HATPase_c#4
475-581 aa · 107 aa · 17.8% of protein
Raw tokenHATPase_c:475:5.86e-17:581:110:109
  • Raw architecture: dCache_1:82:0.00000000281:278:206:195#HAMP:297:0.0000579:358:62:69#His_kinase:380:6.57e-34:459:80:80#HATPase_c:475:5.86e-17:581:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_009718405::NZ_WNAK01000020.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span52601-55991Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGMD29_10935RefSeq proteinWP_082413759.1
Context group IDGCF_009718405::NZ_WNAK01000020.1::G00010
Context members
GMD29_RS10960GMD29_RS10965
Partner locus tags
GMD29_RS10960GMD29_RS10965
Partner old locus tags
GMD29_10935GMD29_10940
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_082413759.1Primary protein accession used for annex mappings.
UniProt accessionA0A0M6WHJ5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0M6WHJ5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGMD29_RS10960Primary locus identifier stored in the genes table.
Old locus tagGMD29_10935Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_WNAK01000020.1Sequence record reported by the local genomic context database.
Genomic interval52 601-54 406 nt1 806 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span52 601-55 991 ntGCF_009718405::NZ_WNAK01000020.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_009718405::NZ_WNAK01000020.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_WNAK01000020.1All displayed genes belong to this local TCS context.
Neighborhood span52 601-55 991 nt3 391 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 601 nt55 991 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GMD29_RS10960GCF_009718405#GMD29_RS10960
HKClassicCurrent focus

52 601-54 406 nt · Reverse (-)

Old locus GMD29_10935RefSeq WP_082413759.1
GMD29_RS10965GCF_009718405#GMD29_RS10965
RRunclassified

54 387-55 991 nt · Reverse (-)

Old locus GMD29_10940RefSeq WP_155177570.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1048005Run 6 · HK · 7 sequences
Representative sequenceGCF_001406815#M72_RS03775Use this link to inspect the representative gene detail.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1048005

Simplified PFAM architecture for HKOC_1048005

PFAM domain coverage: 414 / 601 aa (68.9%)

1 aa601 aa
dCache_1: 48-277 aadCache_1His_kinase: 381-459 aaHis_kinaseHATPase_c: 477-581 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[48-277] | His_kinase[381-459] | HATPase_c[477-581]
  • Domain count: 3
  • Matched identifier: HKOC_1048005
  • Positioned domains: dCache_1 48-277 ; His_kinase 381-459 ; HATPase_c 477-581
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406815#M72_RS03775

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 301 302 · GCF_009718405
AssemblyASM971840v1 · Scaffoldhaploid
Genome composition3 583 549 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 107 · HK 46 · RR 59CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key