Gene detail

GMD29_RS02475

Histidine kinase, Classic

Roseburia faecis · GCF_009718405

ClassHKTypeClassicLength480 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009718405#GMD29_RS02475Stable P2CS identifier used across views.
GenomeGCF_009718405Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1622272Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_155176865.1 · A0A844KNL1 · MIST4 GMD29_RS02475RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length480 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage240 / 480 aa (50.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa480 aa
HAMP: 183-244 aa (62 aa)1HisKA: 251-315 aa (65 aa)2HATPase_c: 363-475 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
183-244 aa · 62 aa · 12.9% of protein
Raw tokenHAMP:183:0.00000000847:244:62:69
2 HisKA#2
251-315 aa · 65 aa · 13.5% of protein
Raw tokenHisKA:251:0.00000000000000103:315:65:64
3 HATPase_c#3
363-475 aa · 113 aa · 23.5% of protein
Raw tokenHATPase_c:363:9.28e-32:475:113:109
  • Raw architecture: HAMP:183:0.00000000847:244:62:69#HisKA:251:0.00000000000000103:315:65:64#HATPase_c:363:9.28e-32:475:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_009718405::NZ_WNAK01000003.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span67719-69853Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGMD29_02470RefSeq proteinWP_155176865.1
Context group IDGCF_009718405::NZ_WNAK01000003.1::G00033
Context members
GMD29_RS02470GMD29_RS02475
Partner locus tags
GMD29_RS02470GMD29_RS02475
Partner old locus tags
GMD29_02465GMD29_02470
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_155176865.1Primary protein accession used for annex mappings.
UniProt accessionA0A844KNL1Primary UniProt accession resolved in the annex database.
UniProt IDA0A844KNL1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGMD29_RS02475Primary locus identifier stored in the genes table.
Old locus tagGMD29_02470Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_WNAK01000003.1Sequence record reported by the local genomic context database.
Genomic interval68 411-69 853 nt1 443 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span67 719-69 853 ntGCF_009718405::NZ_WNAK01000003.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_009718405::NZ_WNAK01000003.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_WNAK01000003.1All displayed genes belong to this local TCS context.
Neighborhood span67 719-69 853 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
67 719 nt69 853 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GMD29_RS02470GCF_009718405#GMD29_RS02470
RROmpR

67 719-68 414 nt · Forward (+)

Old locus GMD29_02465RefSeq WP_155176867.1
GMD29_RS02475GCF_009718405#GMD29_RS02475
HKClassicCurrent focus

68 411-69 853 nt · Forward (+)

Old locus GMD29_02470RefSeq WP_155176865.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1622272Run 6 · HK · 5 sequences
Representative sequenceGCF_009718405#GMD29_RS02475The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1622272

Simplified PFAM architecture for HKOC_1622272

PFAM domain coverage: 219 / 480 aa (45.6%)

1 aa480 aa
HAMP: 201-244 aaHAMPHisKA: 251-314 aaHisKAHATPase_c: 364-474 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[201-244] | HisKA[251-314] | HATPase_c[364-474]
  • Domain count: 3
  • Matched identifier: HKOC_1622272
  • Positioned domains: HAMP 201-244 ; HisKA 251-314 ; HATPase_c 364-474
Cluster members and taxonomy
Visualization

Representative gene: GCF_009718405#GMD29_RS02475

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 301 302 · GCF_009718405
AssemblyASM971840v1 · Scaffoldhaploid
Genome composition3 583 549 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 107 · HK 46 · RR 59CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key