Gene detail

GMD29_RS10570

Histidine kinase, Classic

Roseburia faecis · GCF_009718405

ClassHKTypeClassicLength607 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009718405#GMD29_RS10570Stable P2CS identifier used across views.
GenomeGCF_009718405Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia
Selected clusterHKOC_1020255Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_155176950.1 · A0A844KPK3 · MIST4 GMD29_RS10570RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length607 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 607 aa (41.8%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa607 aa
HAMP: 289-358 aa (70 aa)1His_kinase: 380-459 aa (80 aa)2HATPase_c: 483-586 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
289-358 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:289:0.00000000549:358:70:69
2 His_kinase#2
380-459 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:380:1.09e-31:459:80:80
3 HATPase_c#3
483-586 aa · 104 aa · 17.1% of protein
Raw tokenHATPase_c:483:0.00000134:586:105:109
  • Raw architecture: HAMP:289:0.00000000549:358:70:69#His_kinase:380:1.09e-31:459:80:80#HATPase_c:483:0.00000134:586:105:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_009718405::NZ_WNAK01000019.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43391-46797Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGMD29_10545RefSeq proteinWP_155176950.1
Context group IDGCF_009718405::NZ_WNAK01000019.1::G00008
Context members
GMD29_RS10565GMD29_RS10570
Partner locus tags
GMD29_RS10565GMD29_RS10570
Partner old locus tags
GMD29_10540GMD29_10545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_155176950.1Primary protein accession used for annex mappings.
UniProt accessionA0A844KPK3Primary UniProt accession resolved in the annex database.
UniProt IDA0A844KPK3_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGMD29_RS10570Primary locus identifier stored in the genes table.
Old locus tagGMD29_10545Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_WNAK01000019.1Sequence record reported by the local genomic context database.
Genomic interval44 974-46 797 nt1 824 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 391-46 797 ntGCF_009718405::NZ_WNAK01000019.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_009718405::NZ_WNAK01000019.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_WNAK01000019.1All displayed genes belong to this local TCS context.
Neighborhood span43 391-46 797 nt3 407 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 391 nt46 797 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GMD29_RS10565GCF_009718405#GMD29_RS10565
RRunclassified

43 391-44 980 nt · Reverse (-)

Old locus GMD29_10540RefSeq WP_155176948.1
GMD29_RS10570GCF_009718405#GMD29_RS10570
HKClassicCurrent focus

44 974-46 797 nt · Reverse (-)

Old locus GMD29_10545RefSeq WP_155176950.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1020255Run 6 · HK · 2 sequences
Representative sequenceGCF_009718405#GMD29_RS10570The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1020255

Simplified PFAM architecture for HKOC_1020255

PFAM domain coverage: 237 / 607 aa (39.0%)

1 aa607 aa
HAMP: 306-356 aaHAMPHis_kinase: 380-459 aaHis_kinaseHATPase_c: 481-586 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[306-356] | His_kinase[380-459] | HATPase_c[481-586]
  • Domain count: 3
  • Matched identifier: HKOC_1020255
  • Positioned domains: HAMP 306-356 ; His_kinase 380-459 ; HATPase_c 481-586
Cluster members and taxonomy
Visualization

Representative gene: GCF_009718405#GMD29_RS10570

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 301 302 · GCF_009718405
AssemblyASM971840v1 · Scaffoldhaploid
Genome composition3 583 549 bp · 43,0% GCRoseburia faecis
Signal transduction countsGenes 107 · HK 46 · RR 59CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusRoseburia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Roseburia

Related genes

Preview from the same derived genome key