Gene detail

F2P57_RS03385

Histidine kinase, Classic

[Clostridium] symbiosum · GCF_008632235

ClassHKTypeClassicLength441 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_008632235#F2P57_RS03385Stable P2CS identifier used across views.
GenomeGCF_008632235Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2063584Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_024738938.1 · A0AAW6B191 · MIST4 F2P57_RS03385RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length441 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage210 / 441 aa (47.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa441 aa
HAMP: 154-223 aa (70 aa)1HisKA: 238-288 aa (51 aa)2HATPase_c: 347-435 aa (89 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
154-223 aa · 70 aa · 15.9% of protein
Raw tokenHAMP:154:0.000000000815:223:70:69
2 HisKA#2
238-288 aa · 51 aa · 11.6% of protein
Raw tokenHisKA:238:0.000000112:288:51:64
3 HATPase_c#3
347-435 aa · 89 aa · 20.2% of protein
Raw tokenHATPase_c:347:0.0000000117:435:105:109
  • Raw architecture: HAMP:154:0.000000000815:223:70:69#HisKA:238:0.000000112:288:51:64#HATPase_c:347:0.0000000117:435:105:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_008632235::NZ_VWSY01000001.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span714046-716071Genomic interval covered by the local TCS group.
Identifiers
Old locus tagF2P57_03385RefSeq proteinWP_024738938.1
Context group IDGCF_008632235::NZ_VWSY01000001.1::G00018
Context members
F2P57_RS03380F2P57_RS03385
Partner locus tags
F2P57_RS03380F2P57_RS03385
Partner old locus tags
F2P57_03380F2P57_03385
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_024738938.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6B191Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6B191_CLOSYDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagF2P57_RS03385Primary locus identifier stored in the genes table.
Old locus tagF2P57_03385Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_VWSY01000001.1Sequence record reported by the local genomic context database.
Genomic interval714 746-716 071 nt1 326 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span714 046-716 071 ntGCF_008632235::NZ_VWSY01000001.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_008632235::NZ_VWSY01000001.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VWSY01000001.1All displayed genes belong to this local TCS context.
Neighborhood span714 046-716 071 nt2 026 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
714 046 nt716 071 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

F2P57_RS03380GCF_008632235#F2P57_RS03380
RROmpR

714 046-714 753 nt · Forward (+)

Old locus F2P57_03380RefSeq WP_003497172.1
F2P57_RS03385GCF_008632235#F2P57_RS03385
HKClassicCurrent focus

714 746-716 071 nt · Forward (+)

Old locus F2P57_03385RefSeq WP_024738938.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2063584Run 6 · HK · 39 sequences
Representative sequenceGCF_003463485#DXA34_RS12950Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2063584

Simplified PFAM architecture for HKOC_2063584

PFAM domain coverage: 112 / 441 aa (25.4%)

1 aa441 aa
HAMP: 173-223 aaHAMPHisKA: 236-296 aaHisKA
HAMPHisKA
  • Simplified architecture: HAMP + HisKA
  • Raw architecture: HAMP[173-223] | HisKA[236-296]
  • Domain count: 2
  • Matched identifier: HKOC_2063584
  • Positioned domains: HAMP 173-223 ; HisKA 236-296
Cluster members and taxonomy
Visualization

Representative gene: GCF_003463485#DXA34_RS12950

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 512 · GCF_008632235
AssemblyASM863223v1 · Scaffoldreference genome · haploid
Genome composition5 072 209 bp · 48,0% GC[Clostridium] symbiosum
Signal transduction countsGenes 115 · HK 58 · RR 54CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key