1 HisKA#1
73-138 aa · 66 aa · 22.6% of protein
Raw token
HisKA:73:0.00000000000000223:138:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM09_RS01340
Histidine kinase, Classic
Clostridioides difficile · GCF_007001725
ClassHKTypeClassicLength292 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007001725#EWM09_RS01340Stable P2CS identifier used across views.
GenomeGCF_007001725Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length292 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage166 / 292 aa (56.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa292 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
188-287 aa · 100 aa · 34.2% of protein
Raw token
HATPase_c:188:0.00000000000000258:287:104:109- Raw architecture: HisKA:73:0.00000000000000223:138:66:64#HATPase_c:188:0.00000000000000258:287:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_007001725::NZ_SEQO01000001.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span316236-317114Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM09_01340RefSeq proteinWP_021414776.1
Context group ID
GCF_007001725::NZ_SEQO01000001.1::G00017Context members
EWM09_RS01340
Partner locus tags
EWM09_RS01340
Partner old locus tags
EWM09_01340
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021414776.1Primary protein accession used for annex mappings.
UniProt accessionA0A414UR52Primary UniProt accession resolved in the annex database.
UniProt IDA0A414UR52_MEDGNDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM09_RS01340Primary locus identifier stored in the genes table.
Old locus tagEWM09_01340Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQO01000001.1Sequence record reported by the local genomic context database.
Genomic interval316 236-317 114 nt879 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span316 236-317 114 ntGCF_007001725::NZ_SEQO01000001.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001725::NZ_SEQO01000001.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQO01000001.1All displayed genes belong to this local TCS context.
Neighborhood span316 236-317 114 nt879 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
316 236 nt317 114 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EWM09_RS01340GCF_007001725#EWM09_RS01340
HKClassicCurrent focus
316 236-317 114 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000451545#QQE_RS02505Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2893954
Simplified PFAM architecture for HKOC_2893954
PFAM domain coverage: 163 / 292 aa (55.8%)
1 aa292 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[74-137] | HATPase_c[187-285]
- Domain count: 2
- Matched identifier: HKOC_2893954
- Positioned domains: HisKA 74-137 ; HATPase_c 187-285
Cluster members and taxonomy
Representative gene: GCF_000451545#QQE_RS02505
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001725
AssemblyASM700172v1 · Contighaploid
Genome composition4 054 377 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key