Gene detail

D1N70_RS02465

Histidine kinase, Classic

Clostridioides difficile · GCF_007000915

ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007000915#D1N70_RS02465Stable P2CS identifier used across views.
GenomeGCF_007000915Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2440982Run 6 · 99 sequences · id 100% · cov 80%
External referencesWP_021367036.1 · A0A069A9I9 · MIST4 D1N70_RS02465RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa400 aa
His_kinase: 205-283 aa (79 aa)1HATPase_c: 300-400 aa (101 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw tokenHis_kinase:205:2.31e-31:283:80:80
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw tokenHATPase_c:300:0.00000000147:400:108:109
  • Raw architecture: His_kinase:205:2.31e-31:283:80:80#HATPase_c:300:0.00000000147:400:108:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007000915::NZ_QWUQ01000002.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span108837-110814Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N70_02465RefSeq proteinWP_021367036.1
Context group IDGCF_007000915::NZ_QWUQ01000002.1::G00040
Context members
D1N70_RS02465D1N70_RS02470
Partner locus tags
D1N70_RS02465D1N70_RS02470
Partner old locus tags
D1N70_02465D1N70_02470
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021367036.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A9I9Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A9I9_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N70_RS02465Primary locus identifier stored in the genes table.
Old locus tagD1N70_02465Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWUQ01000002.1Sequence record reported by the local genomic context database.
Genomic interval108 837-110 039 nt1 203 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span108 837-110 814 ntGCF_007000915::NZ_QWUQ01000002.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007000915::NZ_QWUQ01000002.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWUQ01000002.1All displayed genes belong to this local TCS context.
Neighborhood span108 837-110 814 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
108 837 nt110 814 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N70_RS02465GCF_007000915#D1N70_RS02465
HKClassicCurrent focus

108 837-110 039 nt · Forward (+)

Old locus D1N70_02465RefSeq WP_021367036.1
D1N70_RS02470GCF_007000915#D1N70_RS02470
RRLytTR

110 044-110 814 nt · Forward (+)

Old locus D1N70_02470RefSeq WP_009897796.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2440982Run 6 · HK · 99 sequences
Representative sequenceGCF_000448765#QC5_RS13140Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2440982

Simplified PFAM architecture for HKOC_2440982

PFAM domain coverage: 342 / 400 aa (85.5%)

1 aa400 aa
5TM-5TMR_LYT: 27-190 aa5TM-5TMR_LYTHis_kinase: 205-281 aaHis_kinaseHATPase_c: 299-399 aaHATPase_c
5TM-5TMR_LYTHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
  • Domain count: 3
  • Matched identifier: HKOC_2440982
  • Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS13140

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 99 total members. Page 1 / 2.

GCF_000448765#QC5_RS13140 (representative)
QC5_RS13140 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000449705#QGM_RS13250
QGM_RS13250 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000452265#C673_RS10390
C673_RS10390 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000452285#C674_RS12845
C674_RS12845 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000452305#C675_RS13185
C675_RS13185 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000452325#C676_RS13210
C676_RS13210 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000473605#QSW_RS13490
QSW_RS13490 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000586575#Y779_RS0113105
Y779_RS0113105 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_000939295#BN1097_RS14525
BN1097_RS14525 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_001192735#AWU81_RS14790
AWU81_RS14790 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_001263655#AWU80_RS09875
AWU80_RS09875 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_001263675#AWU78_RS14410
AWU78_RS14410 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_001263695#AWU79_RS03830
AWU79_RS03830 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_002301075#BGU05_RS00005
BGU05_RS00005 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_002301105#BGU08_RS00290
BGU08_RS00290 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_002302885#BGV09_RS17370
BGV09_RS17370 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_002303125#BGV22_RS11920
BGV22_RS11920 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_003481905#CDIF29688_RS14560
CDIF29688_RS14560 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004314925#E0O72_RS15515
E0O72_RS15515 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004315705#E0P69_RS06395
E0P69_RS06395 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004315945#E0P54_RS11545
E0P54_RS11545 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004316725#E0Q14_RS05685
E0Q14_RS05685 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004317945#E0Q65_RS17180
E0Q65_RS17180 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004318205#E0Q88_RS17210
E0Q88_RS17210 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_004319125#E0R36_RS15430
E0R36_RS15430 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007000675#D1N83_RS07785
D1N83_RS07785 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007000845#D1N73_RS07000
D1N73_RS07000 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007000915#D1N70_RS02465
D1N70_RS02465 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007000925#D1N68_RS14730
D1N68_RS14730 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007000965#D1N69_RS12105
D1N69_RS12105 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_007001195#D1N57_RS10540
D1N57_RS10540 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_012030135#GSQ49_RS05945
GSQ49_RS05945 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_017310965#JQS20_RS04850
JQS20_RS04850 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_019426605#K1N11_RS01635
K1N11_RS01635 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_021283725#LWE87_RS12165
LWE87_RS12165 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_021283905#LWE93_RS08610
LWE93_RS08610 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_021284005#LWE88_RS11815
LWE88_RS11815 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_024451165#NO136_RS02670
NO136_RS02670 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_025135955#CDIF104450_RS14270
CDIF104450_RS14270 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_025533115#H3U19_RS02660
H3U19_RS02660 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_026337815#OSC44_RS12985
OSC44_RS12985 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_030251305#QQO58_RS04625
QQO58_RS04625 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_030251745#QQO64_RS14670
QQO64_RS14670 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_034188805#SQ131_RS02675
SQ131_RS02675 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_036698425#LFB09_RS02665
LFB09_RS02665 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_036698795#LFB08_RS02810
LFB08_RS02810 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_038752525#ABCQ89_RS16720
ABCQ89_RS16720 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_042876425#ACFYIC_RS04290
ACFYIC_RS04290 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_043107605#ACGAK4_RS03815
ACGAK4_RS03815 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9
GCF_043107725#ACGAK8_RS00585
ACGAK8_RS00585 · HK · Classic
RefSeq: WP_021367036.1
UniProt: A0A069A9I9

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007000915
AssemblyASM700091v1 · Contighaploid
Genome composition4 140 550 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key