1 HisKA#1
78-147 aa · 70 aa · 21.0% of protein
Raw token
HisKA:78:0.000000000000013:147:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0R11_RS04025
Histidine kinase, Classic
Clostridioides difficile · GCF_004318545
ClassHKTypeClassicLength333 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004318545#E0R11_RS04025Stable P2CS identifier used across views.
GenomeGCF_004318545Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length333 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage181 / 333 aa (54.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
194-304 aa · 111 aa · 33.3% of protein
Raw token
HATPase_c:194:8.04e-28:304:111:109- Raw architecture: HisKA:78:0.000000000000013:147:70:64#HATPase_c:194:8.04e-28:304:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004318545::NZ_BIWE01000023.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span21867-22868Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004318545::NZ_BIWE01000023.1::G00005Context members
E0R11_RS04025
Partner locus tags
E0R11_RS04025
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_307721479.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0R11_RS04025Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIWE01000023.1Sequence record reported by the local genomic context database.
Genomic interval21 867-22 868 nt1 002 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span21 867-22 868 ntGCF_004318545::NZ_BIWE01000023.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004318545::NZ_BIWE01000023.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIWE01000023.1All displayed genes belong to this local TCS context.
Neighborhood span21 867-22 868 nt1 002 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 867 nt22 868 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0R11_RS04025GCF_004318545#E0R11_RS04025
HKClassicCurrent focus
21 867-22 868 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004318545#E0R11_RS04025The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2852066
Simplified PFAM architecture for HKOC_2852066
PFAM domain coverage: 234 / 333 aa (70.3%)
1 aa333 aa
PAS_4HisKAHATPase_c
- Simplified architecture: PAS_4 + HisKA + HATPase_c
- Raw architecture: PAS_4[17-69] | HisKA[78-147] | HATPase_c[194-304]
- Domain count: 3
- Matched identifier: HKOC_2852066
- Positioned domains: PAS_4 17-69 ; HisKA 78-147 ; HATPase_c 194-304
Cluster members and taxonomy
Representative gene: GCF_004318545#E0R11_RS04025
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004318545
AssemblyASM431854v1 · Scaffoldhaploid
Genome composition3 928 133 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 44 · RR 45CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key