Gene detail

E0N99_RS13445

Response regulator, unclassified

Clostridioides difficile · GCF_004314305

ClassRRTypeunclassifiedLength356 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314305#E0N99_RS13445Stable P2CS identifier used across views.
GenomeGCF_004314305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0333905Run 7 · 1091 sequences · id 100% · cov 80%
External referencesWP_131005007.1 · MIST4 E0N99_RS13445RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5
Protein length356 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage231 / 356 aa (64.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa356 aa
Response_reg: 3-114 aa (112 aa)1AAA_5: 157-275 aa (119 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
3-114 aa · 112 aa · 31.5% of protein
Raw tokenResponse_reg:3:6.36e-26:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 33.4% of protein
Raw tokenAAA_5:157:0.00000000184:275:128:135
  • Raw architecture: Response_reg:3:6.36e-26:114:112:111#AAA_5:157:0.00000000184:275:128:135
  • Domain description: 1 Response_reg,1 AAA_5
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004314305::NZ_BIOA01000141.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6749-9810Genomic interval covered by the local TCS group.
Context group IDGCF_004314305::NZ_BIOA01000141.1::G00036
Context members
E0N99_RS13440E0N99_RS13445
Partner locus tags
E0N99_RS13440E0N99_RS13445
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131005007.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0N99_RS13445Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOA01000141.1Sequence record reported by the local genomic context database.
Genomic interval8 743-9 810 nt1 068 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span6 749-9 810 ntGCF_004314305::NZ_BIOA01000141.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314305::NZ_BIOA01000141.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOA01000141.1All displayed genes belong to this local TCS context.
Neighborhood span6 749-9 810 nt3 062 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 749 nt9 810 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

E0N99_RS13440GCF_004314305#E0N99_RS13440
HKClassic

6 749-8 743 nt · Forward (+)

RefSeq WP_011861320.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0333905Run 7 · RR · 1091 sequences
Representative sequenceGCF_000003215#QAC_RS0208990Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0333905

Simplified PFAM architecture for RROC_0333905

PFAM domain coverage: 386 / 440 aa (87.7%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regResponse_reg: 3-113 aaResponse_regSigma54_activat: 137-300 aaSigma54_activatSigma54_activat: 137-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14AAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[137-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0333905
  • Positioned domains: Response_reg 3-113 ; Response_reg 3-113 ; Sigma54_activat 137-300 ; Sigma54_activat 137-300 ; AAA_lid_14 306-375 ; AAA_lid_14 306-375 ; HTH_8 397-437 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208990

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314305
AssemblyASM431430v1 · Scaffoldhaploid
Genome composition4 128 237 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key