1 HisKA#1
207-272 aa · 66 aa · 15.3% of protein
Raw token
HisKA:207:0.0000000000000368:272:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N99_RS00075
Histidine kinase, Classic
Clostridioides difficile · GCF_004314305
ClassHKTypeClassicLength430 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314305#E0N99_RS00075Stable P2CS identifier used across views.
GenomeGCF_004314305Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length430 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 430 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa430 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
320-430 aa · 111 aa · 25.8% of protein
Raw token
HATPase_c:320:7.5e-28:430:111:109- Raw architecture: HisKA:207:0.0000000000000368:272:66:64#HATPase_c:320:7.5e-28:430:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314305::NZ_BIOA01000001.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8730-10702Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314305::NZ_BIOA01000001.1::G00001Context members
E0N99_RS00070E0N99_RS00075
Partner locus tags
E0N99_RS00070E0N99_RS00075
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_059026949.1Primary protein accession used for annex mappings.
UniProt accessionA0ABT2TGS9Primary UniProt accession resolved in the annex database.
UniProt IDA0ABT2TGS9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N99_RS00075Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOA01000001.1Sequence record reported by the local genomic context database.
Genomic interval9 410-10 702 nt1 293 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 730-10 702 ntGCF_004314305::NZ_BIOA01000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314305::NZ_BIOA01000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOA01000001.1All displayed genes belong to this local TCS context.
Neighborhood span8 730-10 702 nt1 973 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 730 nt10 702 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0N99_RS00070GCF_004314305#E0N99_RS00070
RROmpR
8 730-9 416 nt · Forward (+)
E0N99_RS00075GCF_004314305#E0N99_RS00075
HKClassicCurrent focus
9 410-10 702 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001497755#BN3430_RS10035Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2172913
Simplified PFAM architecture for HKOC_2172913
PFAM domain coverage: 174 / 430 aa (40.5%)
1 aa430 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[208-272] | HATPase_c[321-429]
- Domain count: 2
- Matched identifier: HKOC_2172913
- Positioned domains: HisKA 208-272 ; HATPase_c 321-429
Cluster members and taxonomy
Representative gene: GCF_001497755#BN3430_RS10035
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314305
AssemblyASM431430v1 · Scaffoldhaploid
Genome composition4 128 237 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key