1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw token
HisKA:185:0.000000000186:250:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGL78_RS00310
Histidine kinase, Classic
Clostridioides difficile · GCF_003932675
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003932675#EGL78_RS00310Stable P2CS identifier used across views.
GenomeGCF_003932675Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw token
HATPase_c:296:8.11e-25:408:113:109- Raw architecture: HisKA:185:0.000000000186:250:66:64#HATPase_c:296:8.11e-25:408:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003932675::NZ_RQZN01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span63269-65162Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL78_00310RefSeq proteinWP_004454470.1
Context group ID
GCF_003932675::NZ_RQZN01000001.1::G00002Context members
EGL78_RS00305EGL78_RS00310
Partner locus tags
EGL78_RS00305EGL78_RS00310
Partner old locus tags
EGL78_00305EGL78_00310
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004454470.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2C6Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2C6_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGL78_RS00310Primary locus identifier stored in the genes table.
Old locus tagEGL78_00310Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZN01000001.1Sequence record reported by the local genomic context database.
Genomic interval63 930-65 162 nt1 233 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span63 269-65 162 ntGCF_003932675::NZ_RQZN01000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003932675::NZ_RQZN01000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZN01000001.1All displayed genes belong to this local TCS context.
Neighborhood span63 269-65 162 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
63 269 nt65 162 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGL78_RS00305GCF_003932675#EGL78_RS00305
RROmpR
63 269-63 940 nt · Forward (+)
EGL78_RS00310GCF_003932675#EGL78_RS00310
HKClassicCurrent focus
63 930-65 162 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004318825#E0R25_RS19155Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2321203
Simplified PFAM architecture for HKOC_2321203
PFAM domain coverage: 178 / 414 aa (43.0%)
1 aa414 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[189-254] | HATPase_c[301-412]
- Domain count: 2
- Matched identifier: HKOC_2321203
- Positioned domains: HisKA 189-254 ; HATPase_c 301-412
Cluster members and taxonomy
Representative gene: GCF_004318825#E0R25_RS19155
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003932675
AssemblyASM393267v1 · Contighaploid
Genome composition4 248 640 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key