Gene detail

EGL81_RS15490

Histidine kinase, Classic

Clostridioides difficile · GCF_003863045

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003863045#EGL81_RS15490Stable P2CS identifier used across views.
GenomeGCF_003863045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503376Run 6 · 181 sequences · id 100% · cov 80%
External referencesWP_003434702.1 · A0A6N3EY23 · MIST4 EGL81_RS15490RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 182-240 aa (59 aa)1HATPase_c: 293-391 aa (99 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000137:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:9.26e-19:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000137:240:59:64#HATPase_c:293:9.26e-19:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003863045::NZ_RQZQ01000034.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span35448-37291Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL81_15490RefSeq proteinWP_003434702.1
Context group IDGCF_003863045::NZ_RQZQ01000034.1::G00054
Context members
EGL81_RS15485EGL81_RS15490
Partner locus tags
EGL81_RS15485EGL81_RS15490
Partner old locus tags
EGL81_15485EGL81_15490
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003434702.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3EY23Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3EY23_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGL81_RS15490Primary locus identifier stored in the genes table.
Old locus tagEGL81_15490Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZQ01000034.1Sequence record reported by the local genomic context database.
Genomic interval36 110-37 291 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span35 448-37 291 ntGCF_003863045::NZ_RQZQ01000034.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863045::NZ_RQZQ01000034.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZQ01000034.1All displayed genes belong to this local TCS context.
Neighborhood span35 448-37 291 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
35 448 nt37 291 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGL81_RS15485GCF_003863045#EGL81_RS15485
RROmpR

35 448-36 110 nt · Forward (+)

Old locus EGL81_15485RefSeq WP_003434705.1
EGL81_RS15490GCF_003863045#EGL81_RS15490
HKClassicCurrent focus

36 110-37 291 nt · Forward (+)

Old locus EGL81_15490RefSeq WP_003434702.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503376Run 6 · HK · 181 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS15375Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503376

Simplified PFAM architecture for HKOC_2503376

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503376
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS15375

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 181 total members. Page 1 / 4.

GCF_000235905#HMPREF9945_RS15375 (representative)
HMPREF9945_RS15375 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000448985#QCC_RS02220
QCC_RS02220 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000449665#QGG_RS02035
QGG_RS02035 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000449685#QGK_RS02315
QGK_RS02315 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000449725#QGO_RS02265
QGO_RS02265 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000451245#QE9_RS02160
QE9_RS02160 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000531295#BN190_RS02360
BN190_RS02360 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_000531535#BN187_RS02650
BN187_RS02650 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_001971945#BER41_RS02630
BER41_RS02630 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_001972085#BER42_RS02685
BER42_RS02685 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002007885#BZ168_RS15880
BZ168_RS15880 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002234355#CGC51_RS02680
CGC51_RS02680 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002300835#BGT93_RS03080
BGT93_RS03080 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002300925#BGT98_RS08270
BGT98_RS08270 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301025#BGU04_RS17655
BGU04_RS17655 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301125#BGU09_RS15645
BGU09_RS15645 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301245#BGU14_RS17940
BGU14_RS17940 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301305#BGU25_RS03060
BGU25_RS03060 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301325#BGU32_RS02825
BGU32_RS02825 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301335#BGU33_RS10845
BGU33_RS10845 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301375#BGU35_RS15395
BGU35_RS15395 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301575#BGU30_RS02575
BGU30_RS02575 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301655#BGU37_RS13515
BGU37_RS13515 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301675#BGU38_RS14715
BGU38_RS14715 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301765#BGU41_RS06270
BGU41_RS06270 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002301805#BGU43_RS12650
BGU43_RS12650 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302005#BGU83_RS14045
BGU83_RS14045 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302125#BGU89_RS06855
BGU89_RS06855 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302225#BGU97_RS15045
BGU97_RS15045 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302245#BGU99_RS13125
BGU99_RS13125 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302265#BGU76_RS01710
BGU76_RS01710 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302305#BGU78_RS12995
BGU78_RS12995 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302465#BGU79_RS09670
BGU79_RS09670 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302745#BGV03_RS02565
BGV03_RS02565 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002302985#BGV14_RS07140
BGV14_RS07140 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002303025#BGV17_RS01235
BGV17_RS01235 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002303245#BGU57_RS07945
BGU57_RS07945 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002303325#BGU54_RS15720
BGU54_RS15720 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002303345#BGU55_RS16330
BGU55_RS16330 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002303715#BGU75_RS12890
BGU75_RS12890 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002304245#BGU98_RS04700
BGU98_RS04700 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002304255#BGU94_RS15730
BGU94_RS15730 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_002812605#CWR56_RS02110
CWR56_RS02110 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003862635#EGM10_RS12735
EGM10_RS12735 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003862765#EGM00_RS15355
EGM00_RS15355 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003862865#EGL96_RS13315
EGL96_RS13315 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003863045#EGL81_RS15490
EGL81_RS15490 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003863235#EGL92_RS14245
EGL92_RS14245 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_003863265#EGL85_RS15460
EGL85_RS15460 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23
GCF_004317745#E0Q70_RS04145
E0Q70_RS04145 · HK · Classic
RefSeq: WP_003434702.1
UniProt: A0A6N3EY23

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863045
AssemblyASM386304v1 · Contighaploid
Genome composition4 020 572 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key