1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw token
HAMP:4:0.0000965:56:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGM06_RS12500
Histidine kinase, Classic
Clostridioides difficile · GCF_003862685
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862685#EGM06_RS12500Stable P2CS identifier used across views.
GenomeGCF_003862685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 305 aa (72.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation3 items
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw token
HisKA:85:0.000000056:150:66:643 HATPase_c#3
202-304 aa · 103 aa · 33.8% of protein
Raw token
HATPase_c:202:1.39e-29:304:103:109- Raw architecture: HAMP:4:0.0000965:56:53:69#HisKA:85:0.000000056:150:66:64#HATPase_c:202:1.39e-29:304:103:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862685::NZ_RRAP01000029.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span24405-26020Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM06_12500RefSeq proteinWP_125018300.1
Context group ID
GCF_003862685::NZ_RRAP01000029.1::G00040Context members
EGM06_RS12495EGM06_RS12500
Partner locus tags
EGM06_RS12495EGM06_RS12500
Partner old locus tags
EGM06_12495EGM06_12500
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_125018300.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGM06_RS12500Primary locus identifier stored in the genes table.
Old locus tagEGM06_12500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAP01000029.1Sequence record reported by the local genomic context database.
Genomic interval25 103-26 020 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span24 405-26 020 ntGCF_003862685::NZ_RRAP01000029.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862685::NZ_RRAP01000029.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAP01000029.1All displayed genes belong to this local TCS context.
Neighborhood span24 405-26 020 nt1 616 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
24 405 nt26 020 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGM06_RS12495GCF_003862685#EGM06_RS12495
RROmpR
24 405-25 097 nt · Forward (+)
EGM06_RS12500GCF_003862685#EGM06_RS12500
HKClassicCurrent focus
25 103-26 020 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003862685#EGM06_RS12500The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882382
Simplified PFAM architecture for HKOC_2882382
PFAM domain coverage: 170 / 305 aa (55.7%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[85-148] | HATPase_c[199-304]
- Domain count: 2
- Matched identifier: HKOC_2882382
- Positioned domains: HisKA 85-148 ; HATPase_c 199-304
Cluster members and taxonomy
Representative gene: GCF_003862685#EGM06_RS12500
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862685
AssemblyASM386268v1 · Contighaploid
Genome composition4 127 337 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key