1 HAMP#1
177-246 aa · 70 aa · 14.7% of protein
Raw token
HAMP:177:0.00000000000000617:246:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA422_RS09500
Histidine kinase, Classic
Clostridioides difficile · GCF_003597895
ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597895#DA422_RS09500Stable P2CS identifier used across views.
GenomeGCF_003597895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 477 aa (50.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa477 aa
Domain-by-domain annotation3 items
2 HisKA#2
253-317 aa · 65 aa · 13.6% of protein
Raw token
HisKA:253:1.04e-16:317:65:643 HATPase_c#3
365-470 aa · 106 aa · 22.2% of protein
Raw token
HATPase_c:365:7.91e-28:470:107:109- Raw architecture: HAMP:177:0.00000000000000617:246:70:69#HisKA:253:1.04e-16:317:65:64#HATPase_c:365:7.91e-28:470:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003597895::NZ_CP028525.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1965479-1967613Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA422_09500RefSeq proteinWP_119957380.1
Context group ID
GCF_003597895::NZ_CP028525.1::G00030Context members
DA422_RS09495DA422_RS09500
Partner locus tags
DA422_RS09495DA422_RS09500
Partner old locus tags
DA422_09495DA422_09500
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_119957380.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA422_RS09500Primary locus identifier stored in the genes table.
Old locus tagDA422_09500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028525.1Sequence record reported by the local genomic context database.
Genomic interval1 966 180-1 967 613 nt1 434 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 965 479-1 967 613 ntGCF_003597895::NZ_CP028525.1::G00030
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597895::NZ_CP028525.1::G00030Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028525.1All displayed genes belong to this local TCS context.
Neighborhood span1 965 479-1 967 613 nt2 135 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 965 479 nt1 967 613 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA422_RS09495GCF_003597895#DA422_RS09495
RROmpR
1 965 479-1 966 177 nt · Forward (+)
DA422_RS09500GCF_003597895#DA422_RS09500
HKClassicCurrent focus
1 966 180-1 967 613 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003597895#DA422_RS09500The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1647697
Simplified PFAM architecture for HKOC_1647697
PFAM domain coverage: 220 / 477 aa (46.1%)
1 aa477 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[197-246] | HisKA[253-316] | HATPase_c[365-470]
- Domain count: 3
- Matched identifier: HKOC_1647697
- Positioned domains: HAMP 197-246 ; HisKA 253-316 ; HATPase_c 365-470
Cluster members and taxonomy
Representative gene: GCF_003597895#DA422_RS09500
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597895
AssemblyASM359789v1 · Chromosomehaploid
Genome composition4 182 371 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key