Gene detail

DA430_RS12065

Histidine kinase, Classic

Clostridioides difficile · GCF_003597815

ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597815#DA430_RS12065Stable P2CS identifier used across views.
GenomeGCF_003597815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355490Run 6 · 348 sequences · id 100% · cov 80%
External referencesWP_009893576.1 · A0AB74R630 · MIST4 DA430_RS12065RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DA430_RS12065
Domain-by-domain annotation2 items
1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw tokenHisKA:309:0.0000000000000134:375:67:64
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw tokenHATPase_c:428:0.0000000388:513:90:109
  • Raw architecture: HisKA:309:0.0000000000000134:375:67:64#HATPase_c:428:0.0000000388:513:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003597815::NZ_CP028527.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2513863-2516140Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA430_12070RefSeq proteinWP_009893576.1
Context group IDGCF_003597815::NZ_CP028527.1::G00038
Context members
DA430_RS12060DA430_RS12065
Partner locus tags
DA430_RS12060DA430_RS12065
Partner old locus tags
DA430_12065DA430_12070
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893576.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R630Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R630_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA430_RS12065Primary locus identifier stored in the genes table.
Old locus tagDA430_12070Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028527.1Sequence record reported by the local genomic context database.
Genomic interval2 514 548-2 516 140 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 513 863-2 516 140 ntGCF_003597815::NZ_CP028527.1::G00038

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597815::NZ_CP028527.1::G00038

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028527.1All displayed genes belong to this local TCS context.
Neighborhood span2 513 863-2 516 140 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 513 863 nt2 516 140 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA430_RS12060GCF_003597815#DA430_RS12060
RROmpR

2 513 863-2 514 579 nt · Forward (+)

Old locus DA430_12065RefSeq WP_009890517.1
DA430_RS12065GCF_003597815#DA430_RS12065
HKClassicCurrent focus

2 514 548-2 516 140 nt · Forward (+)

Old locus DA430_12070RefSeq WP_009893576.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355490Run 6 · HK · 348 sequences
Representative sequenceGCF_000003215#QAC_RS0211650Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355490

Simplified PFAM architecture for HKOC_1355490

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355490
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0211650

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 348 total members. Page 1 / 7.

GCF_000003215#QAC_RS0211650 (representative)
QAC_RS0211650 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000027105#CDR20291_RS12035
CDR20291_RS12035 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000085225#CD196_RS11750
CD196_RS11750 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000154645#UAA_RS0213540
UAA_RS0213540 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000154665#QAD_RS0211810
QAD_RS0211810 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000154685#AEC_RS0213125
AEC_RS0213125 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000155045#EAA_RS0211550
EAA_RS0211550 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000210455#CD7855_RS11540
CD7855_RS11540 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000211235#CDBI1_RS11635
CDBI1_RS11635 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000450145#QK3_RS11955
QK3_RS11955 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000450765#QO5_RS12320
QO5_RS12320 · HK · Classic
RefSeq: WP_021407307.1
GCF_000451065#QSC_RS11395
QSC_RS11395 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000451785#QSO_RS11380
QSO_RS11380 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000451885#QU5_RS11465
QU5_RS11465 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000530295#BN174_RS11270
BN174_RS11270 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000531255#BN173_RS11270
BN173_RS11270 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000531785#BN176_RS11410
BN176_RS11410 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_000826625#BN2378_RS00995
BN2378_RS00995 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_001484885#CD26A54R_RS11570
CD26A54R_RS11570 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_001484895#CD26A54S_RS11685
CD26A54S_RS11685 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_001857645#HMPREF3082_RS00775
HMPREF3082_RS00775 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_001971835#BER28_RS12005
BER28_RS12005 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_001972015#BER29_RS11950
BER29_RS11950 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002300855#BGT96_RS02625
BGT96_RS02625 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002301945#BGU80_RS05185
BGU80_RS05185 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002302755#BGV00_RS01435
BGV00_RS01435 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002302765#BGV01_RS10145
BGV01_RS10145 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002303165#BGV24_RS10855
BGV24_RS10855 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002335485#NCKUH21_RS11420
NCKUH21_RS11420 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002812585#CWR57_RS11385
CWR57_RS11385 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002891495#AMR93_RS10305
AMR93_RS10305 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945415#C3W74_RS12060
C3W74_RS12060 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945515#C3L34_RS12545
C3L34_RS12545 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945665#C3347_RS12060
C3347_RS12060 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945755#C3348_RS12065
C3348_RS12065 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945855#C3350_RS12075
C3350_RS12075 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002945945#C3349_RS12065
C3349_RS12065 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002946035#C3351_RS12070
C3351_RS12070 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002946135#C3352_RS12070
C3352_RS12070 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002946195#C3353_RS12060
C3353_RS12060 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_002954285#AMR92_RS12750
AMR92_RS12750 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003313545#CDIF27638_RS12070
CDIF27638_RS12070 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003313585#CDIF27640_RS12060
CDIF27640_RS12060 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003597795#DA426_RS07845
DA426_RS07845 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003597815#DA430_RS12065
DA430_RS12065 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003597835#DA432_RS12020
DA432_RS12020 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003597895#DA422_RS11830
DA422_RS11830 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003597915#DA436_RS12015
DA436_RS12015 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003625415#C0215_RS13730
C0215_RS13730 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630
GCF_003625425#C0983_RS17925
C0983_RS17925 · HK · Classic
RefSeq: WP_009893576.1
UniProt: A0AB74R630

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597815
AssemblyASM359781v1 · Chromosomehaploid
Genome composition4 174 373 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key