Gene detail

QO5_RS12320

Histidine kinase, Classic

Clostridioides difficile F253 · GCF_000450765

ClassHKTypeClassicLength362 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000450765#QO5_RS12320Stable P2CS identifier used across views.
GenomeGCF_000450765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1355490Run 6 · 348 sequences · id 100% · cov 80%
External referencesWP_021407307.1 · MIST4 QO5_RS12320RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length362 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 362 aa (42.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QO5_RS12320
Domain-by-domain annotation2 items
1 HisKA#1
141-207 aa · 67 aa · 18.5% of protein
Raw tokenHisKA:141:0.0000000000000171:207:67:64
2 HATPase_c#2
260-345 aa · 86 aa · 23.8% of protein
Raw tokenHATPase_c:260:0.0000000536:345:90:109
  • Raw architecture: HisKA:141:0.0000000000000171:207:67:64#HATPase_c:260:0.0000000536:345:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000450765::NZ_AVKO01000307.1::G00041
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1091Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQO5_2441RefSeq proteinWP_021407307.1
Context group IDGCF_000450765::NZ_AVKO01000307.1::G00041
Context members
QO5_RS12320
Partner locus tags
QO5_RS12320
Partner old locus tags
QO5_2441
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021407307.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQO5_RS12320Primary locus identifier stored in the genes table.
Old locus tagQO5_2441Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVKO01000307.1Sequence record reported by the local genomic context database.
Genomic interval1-1 091 nt1 091 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 091 ntGCF_000450765::NZ_AVKO01000307.1::G00041

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000450765::NZ_AVKO01000307.1::G00041

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVKO01000307.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 091 nt1 091 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 091 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

QO5_RS12320GCF_000450765#QO5_RS12320
HKClassicCurrent focus

1-1 091 nt · Forward (+)

Old locus QO5_2441RefSeq WP_021407307.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1355490Run 6 · HK · 348 sequences
Representative sequenceGCF_000003215#QAC_RS0211650Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1355490

Simplified PFAM architecture for HKOC_1355490

PFAM domain coverage: 191 / 530 aa (36.0%)

1 aa530 aa
HAMP: 255-295 aaHAMPHisKA: 310-375 aaHisKAHATPase_c: 427-510 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
  • Domain count: 3
  • Matched identifier: HKOC_1355490
  • Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0211650

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 367 · GCF_000450765
AssemblyASM45076v2 · Contighaploid
Genome composition4 056 592 bp · 28,5% GCClostridioides difficile F253
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key