Gene detail

KGMB01110_RS14045

Histidine kinase, Classic

Mediterraneibacter butyricigenes · GCF_003574295

ClassHKTypeClassicLength356 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003574295#KGMB01110_RS14045Stable P2CS identifier used across views.
GenomeGCF_003574295Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_2771468Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_119298966.1 · A0A391PEP2 · MIST4 KGMB01110_RS14045RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length356 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 356 aa (49.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa356 aa
HisKA: 136-203 aa (68 aa)1HATPase_c: 247-355 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
136-203 aa · 68 aa · 19.1% of protein
Raw tokenHisKA:136:0.0000000000432:203:68:64
2 HATPase_c#2
247-355 aa · 109 aa · 30.6% of protein
Raw tokenHATPase_c:247:9.47e-23:355:110:109
  • Raw architecture: HisKA:136:0.0000000000432:203:68:64#HATPase_c:247:9.47e-23:355:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003574295::NZ_BHGK01000001.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2868697-2870502Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKGMB01110_27650RefSeq proteinWP_119298966.1
Context group IDGCF_003574295::NZ_BHGK01000001.1::G00032
Context members
KGMB01110_RS14040KGMB01110_RS14045
Partner locus tags
KGMB01110_RS14040KGMB01110_RS14045
Partner old locus tags
KGMB01110_27640KGMB01110_27650
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_119298966.1Primary protein accession used for annex mappings.
UniProt accessionA0A391PEP2Primary UniProt accession resolved in the annex database.
UniProt IDA0A391PEP2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKGMB01110_RS14045Primary locus identifier stored in the genes table.
Old locus tagKGMB01110_27650Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BHGK01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 869 432-2 870 502 nt1 071 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 868 697-2 870 502 ntGCF_003574295::NZ_BHGK01000001.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003574295::NZ_BHGK01000001.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BHGK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 868 697-2 870 502 nt1 806 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 868 697 nt2 870 502 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KGMB01110_RS14040GCF_003574295#KGMB01110_RS14040
RROmpR

2 868 697-2 869 416 nt · Reverse (-)

Old locus KGMB01110_27640RefSeq WP_119298964.1
KGMB01110_RS14045GCF_003574295#KGMB01110_RS14045
HKClassicCurrent focus

2 869 432-2 870 502 nt · Reverse (-)

Old locus KGMB01110_27650RefSeq WP_119298966.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2771468Run 6 · HK · 1 sequences
Representative sequenceGCF_003574295#KGMB01110_RS14045The current gene is the representative for this cluster.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2771468

Simplified PFAM architecture for HKOC_2771468

PFAM domain coverage: 285 / 356 aa (80.1%)

1 aa356 aa
DUF4118: 14-123 aaDUF4118HisKA: 136-202 aaHisKAHATPase_c: 248-355 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[14-123] | HisKA[136-202] | HATPase_c[248-355]
  • Domain count: 3
  • Matched identifier: HKOC_2771468
  • Positioned domains: DUF4118 14-123 ; HisKA 136-202 ; HATPase_c 248-355
Cluster members and taxonomy
Visualization

Representative gene: GCF_003574295#KGMB01110_RS14045

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 316 025 · GCF_003574295
AssemblyASM357429v1 · Contigreference genome · haploid
Genome composition3 034 489 bp · 44,0% GCMediterraneibacter butyricigenes
Signal transduction countsGenes 58 · HK 29 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key