Gene detail

KGMB01110_RS12260

Histidine kinase, Classic

Mediterraneibacter butyricigenes · GCF_003574295

ClassHKTypeClassicLength385 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003574295#KGMB01110_RS12260Stable P2CS identifier used across views.
GenomeGCF_003574295Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_2566651Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_119298577.1 · A0A391PAD5 · MIST4 KGMB01110_RS12260RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length385 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 385 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa385 aa
HAMP: 89-159 aa (71 aa)1HisKA: 164-230 aa (67 aa)2HATPase_c: 272-380 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
89-159 aa · 71 aa · 18.4% of protein
Raw tokenHAMP:89:0.000000000116:159:71:69
2 HisKA#2
164-230 aa · 67 aa · 17.4% of protein
Raw tokenHisKA:164:0.000000000376:230:67:64
3 HATPase_c#3
272-380 aa · 109 aa · 28.3% of protein
Raw tokenHATPase_c:272:2.46e-31:380:109:109
  • Raw architecture: HAMP:89:0.000000000116:159:71:69#HisKA:164:0.000000000376:230:67:64#HATPase_c:272:2.46e-31:380:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003574295::NZ_BHGK01000001.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2499257-2501091Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKGMB01110_23940RefSeq proteinWP_119298577.1
Context group IDGCF_003574295::NZ_BHGK01000001.1::G00026
Context members
KGMB01110_RS12260KGMB01110_RS12265
Partner locus tags
KGMB01110_RS12260KGMB01110_RS12265
Partner old locus tags
KGMB01110_23940KGMB01110_23950
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_119298577.1Primary protein accession used for annex mappings.
UniProt accessionA0A391PAD5Primary UniProt accession resolved in the annex database.
UniProt IDA0A391PAD5_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKGMB01110_RS12260Primary locus identifier stored in the genes table.
Old locus tagKGMB01110_23940Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BHGK01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 499 257-2 500 414 nt1 158 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 499 257-2 501 091 ntGCF_003574295::NZ_BHGK01000001.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003574295::NZ_BHGK01000001.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BHGK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 499 257-2 501 091 nt1 835 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 499 257 nt2 501 091 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KGMB01110_RS12260GCF_003574295#KGMB01110_RS12260
HKClassicCurrent focus

2 499 257-2 500 414 nt · Reverse (-)

Old locus KGMB01110_23940RefSeq WP_119298577.1
KGMB01110_RS12265GCF_003574295#KGMB01110_RS12265
RROmpR

2 500 411-2 501 091 nt · Reverse (-)

Old locus KGMB01110_23950RefSeq WP_022024520.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2566651Run 6 · HK · 1 sequences
Representative sequenceGCF_003574295#KGMB01110_RS12260The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2566651

Simplified PFAM architecture for HKOC_2566651

PFAM domain coverage: 226 / 385 aa (58.7%)

1 aa385 aa
HAMP: 106-158 aaHAMPHisKA: 164-229 aaHisKAHATPase_c: 275-381 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-158] | HisKA[164-229] | HATPase_c[275-381]
  • Domain count: 3
  • Matched identifier: HKOC_2566651
  • Positioned domains: HAMP 106-158 ; HisKA 164-229 ; HATPase_c 275-381
Cluster members and taxonomy
Visualization

Representative gene: GCF_003574295#KGMB01110_RS12260

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 316 025 · GCF_003574295
AssemblyASM357429v1 · Contigreference genome · haploid
Genome composition3 034 489 bp · 44,0% GCMediterraneibacter butyricigenes
Signal transduction countsGenes 58 · HK 29 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key