Gene detail

KGMB01110_RS12000

Histidine kinase, Classic

Mediterraneibacter butyricigenes · GCF_003574295

ClassHKTypeClassicLength445 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003574295#KGMB01110_RS12000Stable P2CS identifier used across views.
GenomeGCF_003574295Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_2024368Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_119298523.1 · A0A391PDX0 · MIST4 KGMB01110_RS12000RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHisKAHATPase_c
Protein length445 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage269 / 445 aa (60.4%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa445 aa
sCache_like: 36-130 aa (95 aa)1HisKA: 218-284 aa (67 aa)2HATPase_c: 333-439 aa (107 aa)3
Domain-by-domain annotation3 items
1 sCache_like#1
36-130 aa · 95 aa · 21.3% of protein
Raw tokensCache_like:36:0.00000000000188:130:101:114
2 HisKA#2
218-284 aa · 67 aa · 15.1% of protein
Raw tokenHisKA:218:2.77e-18:284:67:64
3 HATPase_c#3
333-439 aa · 107 aa · 24.0% of protein
Raw tokenHATPase_c:333:1.67e-27:439:107:109
  • Raw architecture: sCache_like:36:0.00000000000188:130:101:114#HisKA:218:2.77e-18:284:67:64#HATPase_c:333:1.67e-27:439:107:109
  • Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003574295::NZ_BHGK01000001.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2437546-2439554Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKGMB01110_23390RefSeq proteinWP_119298523.1
Context group IDGCF_003574295::NZ_BHGK01000001.1::G00025
Context members
KGMB01110_RS11995KGMB01110_RS12000
Partner locus tags
KGMB01110_RS11995KGMB01110_RS12000
Partner old locus tags
KGMB01110_23380KGMB01110_23390
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_119298523.1Primary protein accession used for annex mappings.
UniProt accessionA0A391PDX0Primary UniProt accession resolved in the annex database.
UniProt IDA0A391PDX0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKGMB01110_RS12000Primary locus identifier stored in the genes table.
Old locus tagKGMB01110_23390Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BHGK01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 438 217-2 439 554 nt1 338 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 437 546-2 439 554 ntGCF_003574295::NZ_BHGK01000001.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003574295::NZ_BHGK01000001.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BHGK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 437 546-2 439 554 nt2 009 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 437 546 nt2 439 554 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KGMB01110_RS11995GCF_003574295#KGMB01110_RS11995
RROmpR

2 437 546-2 438 220 nt · Forward (+)

Old locus KGMB01110_23380RefSeq WP_119298521.1
KGMB01110_RS12000GCF_003574295#KGMB01110_RS12000
HKClassicCurrent focus

2 438 217-2 439 554 nt · Forward (+)

Old locus KGMB01110_23390RefSeq WP_119298523.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2024368Run 6 · HK · 1 sequences
Representative sequenceGCF_003574295#KGMB01110_RS12000The current gene is the representative for this cluster.
PFAM architecturesCache_like + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2024368

Simplified PFAM architecture for HKOC_2024368

PFAM domain coverage: 270 / 445 aa (60.7%)

1 aa445 aa
sCache_like: 37-131 aasCache_likeHisKA: 218-284 aaHisKAHATPase_c: 332-439 aaHATPase_c
sCache_likeHisKAHATPase_c
  • Simplified architecture: sCache_like + HisKA + HATPase_c
  • Raw architecture: sCache_like[37-131] | HisKA[218-284] | HATPase_c[332-439]
  • Domain count: 3
  • Matched identifier: HKOC_2024368
  • Positioned domains: sCache_like 37-131 ; HisKA 218-284 ; HATPase_c 332-439
Cluster members and taxonomy
Visualization

Representative gene: GCF_003574295#KGMB01110_RS12000

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 316 025 · GCF_003574295
AssemblyASM357429v1 · Contigreference genome · haploid
Genome composition3 034 489 bp · 44,0% GCMediterraneibacter butyricigenes
Signal transduction countsGenes 58 · HK 29 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key