Gene detail

KGMB01110_RS02060

Histidine kinase, Hybrid

Mediterraneibacter butyricigenes · GCF_003574295

ClassHKTypeHybridLength872 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003574295#KGMB01110_RS02060Stable P2CS identifier used across views.
GenomeGCF_003574295Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_0456602Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_119297398.1 · A0A391P5B9 · MIST4 KGMB01110_RS02060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAFHisKAHATPase_cResponse_reg
Protein length872 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage438 / 872 aa (50.2%)Merged over positioned domains only.
Domain description1 GAF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa872 aa
GAF: 35-172 aa (138 aa)1HisKA: 487-553 aa (67 aa)2HATPase_c: 601-717 aa (117 aa)3Response_reg: 748-863 aa (116 aa)4
Domain-by-domain annotation4 items
1 GAF#1
35-172 aa · 138 aa · 15.8% of protein
Raw tokenGAF:35:0.0000167:172:138:133
2 HisKA#2
487-553 aa · 67 aa · 7.7% of protein
Raw tokenHisKA:487:0.00000000000000225:553:67:64
3 HATPase_c#3
601-717 aa · 117 aa · 13.4% of protein
Raw tokenHATPase_c:601:7.43e-25:717:117:109
4 Response_reg#4
748-863 aa · 116 aa · 13.3% of protein
Raw tokenResponse_reg:748:5.87e-24:863:116:111
  • Raw architecture: GAF:35:0.0000167:172:138:133#HisKA:487:0.00000000000000225:553:67:64#HATPase_c:601:7.43e-25:717:117:109#Response_reg:748:5.87e-24:863:116:111
  • Domain description: 1 GAF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003574295::NZ_BHGK01000001.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span428517-431135Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKGMB01110_04040RefSeq proteinWP_119297398.1
Context group IDGCF_003574295::NZ_BHGK01000001.1::G00002
Context members
KGMB01110_RS02060
Partner locus tags
KGMB01110_RS02060
Partner old locus tags
KGMB01110_04040
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_119297398.1Primary protein accession used for annex mappings.
UniProt accessionA0A391P5B9Primary UniProt accession resolved in the annex database.
UniProt IDA0A391P5B9_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKGMB01110_RS02060Primary locus identifier stored in the genes table.
Old locus tagKGMB01110_04040Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BHGK01000001.1Sequence record reported by the local genomic context database.
Genomic interval428 517-431 135 nt2 619 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span428 517-431 135 ntGCF_003574295::NZ_BHGK01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003574295::NZ_BHGK01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BHGK01000001.1All displayed genes belong to this local TCS context.
Neighborhood span428 517-431 135 nt2 619 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
428 517 nt431 135 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0456602Run 6 · HK · 1 sequences
Representative sequenceGCF_003574295#KGMB01110_RS02060The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0456602

Simplified PFAM architecture for HKOC_0456602

PFAM domain coverage: 298 / 872 aa (34.2%)

1 aa872 aa
HisKA: 487-553 aaHisKAHATPase_c: 601-715 aaHATPase_cResponse_reg: 748-863 aaResponse_reg
HisKAHATPase_cResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg
  • Raw architecture: HisKA[487-553] | HATPase_c[601-715] | Response_reg[748-863]
  • Domain count: 3
  • Matched identifier: HKOC_0456602
  • Positioned domains: HisKA 487-553 ; HATPase_c 601-715 ; Response_reg 748-863
Cluster members and taxonomy
Visualization

Representative gene: GCF_003574295#KGMB01110_RS02060

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 316 025 · GCF_003574295
AssemblyASM357429v1 · Contigreference genome · haploid
Genome composition3 034 489 bp · 44,0% GCMediterraneibacter butyricigenes
Signal transduction countsGenes 58 · HK 29 · RR 28CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key