Gene detail

CDIF28196_RS17795

Histidine kinase, Classic

Clostridioides difficile · GCF_003482035

ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003482035#CDIF28196_RS17795Stable P2CS identifier used across views.
GenomeGCF_003482035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2082201Run 6 · 595 sequences · id 100% · cov 80%
External referencesWP_009889841.1 · Q187J0 · MIST4 CDIF28196_RS17795RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
HAMP: 144-211 aa (68 aa)1HisKA: 232-296 aa (65 aa)2HATPase_c: 342-419 aa (78 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw tokenHAMP:144:0.000000211:211:68:69
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw tokenHisKA:232:0.0000048:296:65:64
3 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw tokenHATPase_c:342:0.00000544:419:90:109
  • Raw architecture: HAMP:144:0.000000211:211:68:69#HisKA:232:0.0000048:296:65:64#HATPase_c:342:0.00000544:419:90:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003482035::NZ_CP012320.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3808033-3810002Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28196_03524RefSeq proteinWP_009889841.1
Context group IDGCF_003482035::NZ_CP012320.1::G00057
Context members
CDIF28196_RS17795CDIF28196_RS17800
Partner locus tags
CDIF28196_RS17795CDIF28196_RS17800
Partner old locus tags
CDIF28196_03524CDIF28196_03525
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889841.1Primary protein accession used for annex mappings.
UniProt accessionQ187J0Primary UniProt accession resolved in the annex database.
UniProt IDQ187J0_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF28196_RS17795Primary locus identifier stored in the genes table.
Old locus tagCDIF28196_03524Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012320.1Sequence record reported by the local genomic context database.
Genomic interval3 808 033-3 809 352 nt1 320 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 808 033-3 810 002 ntGCF_003482035::NZ_CP012320.1::G00057

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003482035::NZ_CP012320.1::G00057

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012320.1All displayed genes belong to this local TCS context.
Neighborhood span3 808 033-3 810 002 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 808 033 nt3 810 002 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF28196_RS17795GCF_003482035#CDIF28196_RS17795
HKClassicCurrent focus

3 808 033-3 809 352 nt · Reverse (-)

Old locus CDIF28196_03524RefSeq WP_009889841.1
CDIF28196_RS17800GCF_003482035#CDIF28196_RS17800
RROmpR

3 809 349-3 810 002 nt · Reverse (-)

Old locus CDIF28196_03525RefSeq WP_009889840.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2082201Run 6 · HK · 595 sequences
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2082201

Simplified PFAM architecture for HKOC_2082201

PFAM domain coverage: 143 / 439 aa (32.6%)

1 aa439 aa
HisKA: 233-296 aaHisKAHATPase_c: 342-420 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[233-296] | HATPase_c[342-420]
  • Domain count: 2
  • Matched identifier: HKOC_2082201
  • Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0217010

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 595 total members. Page 1 / 12.

GCF_000003215#QAC_RS0217010 (representative)
QAC_RS0217010 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000009205#CD630_RS10205
CD630_RS10205 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000027105#CDR20291_RS09940
CDR20291_RS09940 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000154685#AEC_RS0218475
AEC_RS0218475 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000210455#CD7855_RS16995
CD7855_RS16995 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000393295#WOK_RS08430
WOK_RS08430 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000424205#G605_RS0116960
G605_RS0116960 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000448885#QAU_RS09325
QAU_RS09325 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000449045#QCI_RS09445
QCI_RS09445 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000449785#QGW_RS17480
QGW_RS17480 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000450765#QO5_RS10150
QO5_RS10150 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451185#QQ3_RS09830
QQ3_RS09830 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451745#QSK_RS17375
QSK_RS17375 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451765#QSM_RS01575
QSM_RS01575 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451785#QSO_RS16660
QSO_RS16660 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451865#QU3_RS17285
QU3_RS17285 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000451885#QU5_RS17130
QU5_RS17130 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000473665#QUO_RS17925
QUO_RS17925 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000531225#BN184_RS02470
BN184_RS02470 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000632735#BG47_RS06085
BG47_RS06085 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000821005#TY67_RS11750
TY67_RS11750 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000826625#BN2378_RS06300
BN2378_RS06300 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000828225#SE46_RS19585
SE46_RS19585 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000828235#SE44_RS04165
SE44_RS04165 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000828255#SE45_RS19200
SE45_RS19200 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000828325#NX98_RS19415
NX98_RS19415 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000932055#CDIF630_RS10445
CDIF630_RS10445 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_000953275#CD630DERM_RS18225
CD630DERM_RS18225 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001484885#CD26A54R_RS16865
CD26A54R_RS16865 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001484895#CD26A54S_RS09560
CD26A54S_RS09560 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001484895#CD26A54S_RS16980
CD26A54S_RS16980 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001497755#BN3430_RS02535
BN3430_RS02535 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001678145#cdgr_RS17455
cdgr_RS17455 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001857645#HMPREF3082_RS00140
HMPREF3082_RS00140 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001971835#BER28_RS17360
BER28_RS17360 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_001972015#BER29_RS17290
BER29_RS17290 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002080065#CDIF630erm_RS18480
CDIF630erm_RS18480 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002082945#A6J96_RS04380
A6J96_RS04380 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002300845#BGT94_RS11410
BGT94_RS11410 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002301035#BGU03_RS03905
BGU03_RS03905 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002301735#BGU40_RS14545
BGU40_RS14545 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002301945#BGU80_RS01505
BGU80_RS01505 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002302085#BGU87_RS02195
BGU87_RS02195 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002302765#BGV01_RS10285
BGV01_RS10285 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002303165#BGV24_RS00405
BGV24_RS00405 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002303415#BGU61_RS02405
BGU61_RS02405 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002303575#BGU68_RS00395
BGU68_RS00395 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002303695#BGU74_RS03875
BGU74_RS03875 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002812585#CWR57_RS16975
CWR57_RS16975 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0
GCF_002940905#AWN78_RS12690
AWN78_RS12690 · HK · Classic
RefSeq: WP_009889841.1
UniProt: Q187J0

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482035
AssemblyASM348203v1 · Complete Genomehaploid
Genome composition4 205 365 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key