1 HAMP#1
144-211 aa · 68 aa · 15.5% of protein
Raw token
HAMP:144:0.000000211:211:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CWR57_RS16975
Histidine kinase, Classic
Clostridioides difficile · GCF_002812585
ClassHKTypeClassicLength439 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002812585#CWR57_RS16975Stable P2CS identifier used across views.
GenomeGCF_002812585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length439 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage211 / 439 aa (48.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa439 aa
Domain-by-domain annotation3 items
2 HisKA#2
232-296 aa · 65 aa · 14.8% of protein
Raw token
HisKA:232:0.0000048:296:65:643 HATPase_c#3
342-419 aa · 78 aa · 17.8% of protein
Raw token
HATPase_c:342:0.00000544:419:90:109- Raw architecture: HAMP:144:0.000000211:211:68:69#HisKA:232:0.0000048:296:65:64#HATPase_c:342:0.00000544:419:90:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002812585::NZ_CP025044.1::G00057
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3681673-3683642Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCWR57_16975RefSeq proteinWP_009889841.1
Context group ID
GCF_002812585::NZ_CP025044.1::G00057Context members
CWR57_RS16975CWR57_RS16980
Partner locus tags
CWR57_RS16975CWR57_RS16980
Partner old locus tags
CWR57_16975CWR57_16980
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009889841.1Primary protein accession used for annex mappings.
UniProt accessionQ187J0Primary UniProt accession resolved in the annex database.
UniProt IDQ187J0_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCWR57_RS16975Primary locus identifier stored in the genes table.
Old locus tagCWR57_16975Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP025044.1Sequence record reported by the local genomic context database.
Genomic interval3 681 673-3 682 992 nt1 320 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 681 673-3 683 642 ntGCF_002812585::NZ_CP025044.1::G00057
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002812585::NZ_CP025044.1::G00057Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP025044.1All displayed genes belong to this local TCS context.
Neighborhood span3 681 673-3 683 642 nt1 970 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 681 673 nt3 683 642 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CWR57_RS16975GCF_002812585#CWR57_RS16975
HKClassicCurrent focus
3 681 673-3 682 992 nt · Reverse (-)
CWR57_RS16980GCF_002812585#CWR57_RS16980
RROmpR
3 682 989-3 683 642 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0217010Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2082201
Simplified PFAM architecture for HKOC_2082201
PFAM domain coverage: 143 / 439 aa (32.6%)
1 aa439 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[233-296] | HATPase_c[342-420]
- Domain count: 2
- Matched identifier: HKOC_2082201
- Positioned domains: HisKA 233-296 ; HATPase_c 342-420
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0217010
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002812585
AssemblyASM281258v1 · Complete Genomehaploid
Genome composition4 190 038 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key