Gene detail

CDIF28196_RS10040

Histidine kinase, Classic

Clostridioides difficile · GCF_003482035

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003482035#CDIF28196_RS10040Stable P2CS identifier used across views.
GenomeGCF_003482035Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1726898Run 6 · 387 sequences · id 100% · cov 80%
External referencesWP_009889869.1 · A0A0H3N7P5 · MIST4 CDIF28196_RS10040RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDIF28196_RS10040
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.49e-36:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.45e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.000000106:467:114:109
  • Raw architecture: H_kinase_N:12:1.49e-36:142:132:139#HisKA_2:276:2.45e-16:350:76:76#HATPase_c:370:0.000000106:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003482035::NZ_CP012320.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2071416-2073393Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF28196_01984RefSeq proteinWP_009889869.1
Context group IDGCF_003482035::NZ_CP012320.1::G00032
Context members
CDIF28196_RS10035CDIF28196_RS10040
Partner locus tags
CDIF28196_RS10035CDIF28196_RS10040
Partner old locus tags
CDIF28196_01983CDIF28196_01984
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889869.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N7P5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N7P5_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF28196_RS10040Primary locus identifier stored in the genes table.
Old locus tagCDIF28196_01984Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP012320.1Sequence record reported by the local genomic context database.
Genomic interval2 071 984-2 073 393 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 071 416-2 073 393 ntGCF_003482035::NZ_CP012320.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003482035::NZ_CP012320.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP012320.1All displayed genes belong to this local TCS context.
Neighborhood span2 071 416-2 073 393 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 071 416 nt2 073 393 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF28196_RS10035GCF_003482035#CDIF28196_RS10035
RRAmiR_NasR

2 071 416-2 071 991 nt · Forward (+)

Old locus CDIF28196_01983RefSeq WP_003423977.1
CDIF28196_RS10040GCF_003482035#CDIF28196_RS10040
HKClassicCurrent focus

2 071 984-2 073 393 nt · Forward (+)

Old locus CDIF28196_01984RefSeq WP_009889869.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1726898Run 6 · HK · 387 sequences
Representative sequenceGCF_000003215#QAC_RS0209635Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1726898

Simplified PFAM architecture for HKOC_1726898

PFAM domain coverage: 302 / 469 aa (64.4%)

1 aa469 aa
GAF_PdtaS: 6-141 aaGAF_PdtaSHisKA_2: 276-347 aaHisKA_2HATPase_c: 373-466 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
  • Domain count: 3
  • Matched identifier: HKOC_1726898
  • Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209635

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 387 total members. Page 1 / 8.

GCF_000003215#QAC_RS0209635 (representative)
QAC_RS0209635 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000027105#CDR20291_RS10055
CDR20291_RS10055 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000085225#CD196_RS09750
CD196_RS09750 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000154645#UAA_RS0211515
UAA_RS0211515 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000154665#QAD_RS0209810
QAD_RS0209810 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000154685#AEC_RS0211125
AEC_RS0211125 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000155045#EAA_RS0209550
EAA_RS0209550 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000210455#CD7855_RS09565
CD7855_RS09565 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000211235#CDBI1_RS09655
CDBI1_RS09655 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000450145#QK3_RS09940
QK3_RS09940 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000450765#QO5_RS10305
QO5_RS10305 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000450785#QO7_RS09490
QO7_RS09490 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000451065#QSC_RS09400
QSC_RS09400 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000451785#QSO_RS08395
QSO_RS08395 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000451885#QU5_RS09465
QU5_RS09465 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000452005#QUI_RS09315
QUI_RS09315 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000530295#BN174_RS09305
BN174_RS09305 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000530795#BN175_RS09500
BN175_RS09500 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000531255#BN173_RS09310
BN173_RS09310 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_000826625#BN2378_RS18195
BN2378_RS18195 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001484885#CD26A54R_RS09575
CD26A54R_RS09575 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001484895#CD26A54S_RS09685
CD26A54S_RS09685 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001857645#HMPREF3082_RS16940
HMPREF3082_RS16940 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001971835#BER28_RS10000
BER28_RS10000 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001971865#BER27_RS09975
BER27_RS09975 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_001972015#BER29_RS09945
BER29_RS09945 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301255#BGU15_RS01880
BGU15_RS01880 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301465#BGU24_RS06800
BGU24_RS06800 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301525#BGU28_RS11380
BGU28_RS11380 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301615#BGU34_RS08470
BGU34_RS08470 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301715#BGU39_RS05305
BGU39_RS05305 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002301945#BGU80_RS17550
BGU80_RS17550 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002302755#BGV00_RS07945
BGV00_RS07945 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002302765#BGV01_RS04130
BGV01_RS04130 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002303105#BGV21_RS16920
BGV21_RS16920 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002303165#BGV24_RS16605
BGV24_RS16605 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002335485#NCKUH21_RS09415
NCKUH21_RS09415 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002812585#CWR57_RS09360
CWR57_RS09360 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002891495#AMR93_RS12240
AMR93_RS12240 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002891615#AMR88_RS11730
AMR88_RS11730 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002891625#AMR90_RS06900
AMR90_RS06900 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945415#C3W74_RS10035
C3W74_RS10035 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945515#C3L34_RS10520
C3L34_RS10520 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945665#C3347_RS10035
C3347_RS10035 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945755#C3348_RS10040
C3348_RS10040 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945855#C3350_RS10050
C3350_RS10050 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002945945#C3349_RS10040
C3349_RS10040 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002946035#C3351_RS10045
C3351_RS10045 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002946135#C3352_RS10045
C3352_RS10045 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5
GCF_002946195#C3353_RS10035
C3353_RS10035 · HK · Classic
RefSeq: WP_009889869.1
UniProt: A0A0H3N7P5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003482035
AssemblyASM348203v1 · Complete Genomehaploid
Genome composition4 205 365 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key