1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw token
H_kinase_N:12:1.49e-36:142:132:139P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CWR57_RS09360
Histidine kinase, Classic
Clostridioides difficile · GCF_002812585
ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002812585#CWR57_RS09360Stable P2CS identifier used across views.
GenomeGCF_002812585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw token
HisKA_2:276:2.45e-16:350:76:763 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw token
HATPase_c:370:0.000000106:467:114:109- Raw architecture: H_kinase_N:12:1.49e-36:142:132:139#HisKA_2:276:2.45e-16:350:76:76#HATPase_c:370:0.000000106:467:114:109
- Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_002812585::NZ_CP025044.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1961917-1963894Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCWR57_09360RefSeq proteinWP_009889869.1
Context group ID
GCF_002812585::NZ_CP025044.1::G00032Context members
CWR57_RS09355CWR57_RS09360
Partner locus tags
CWR57_RS09355CWR57_RS09360
Partner old locus tags
CWR57_09355CWR57_09360
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009889869.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N7P5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N7P5_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCWR57_RS09360Primary locus identifier stored in the genes table.
Old locus tagCWR57_09360Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP025044.1Sequence record reported by the local genomic context database.
Genomic interval1 962 485-1 963 894 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 961 917-1 963 894 ntGCF_002812585::NZ_CP025044.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002812585::NZ_CP025044.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP025044.1All displayed genes belong to this local TCS context.
Neighborhood span1 961 917-1 963 894 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 961 917 nt1 963 894 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CWR57_RS09355GCF_002812585#CWR57_RS09355
RRAmiR_NasR
1 961 917-1 962 492 nt · Forward (+)
CWR57_RS09360GCF_002812585#CWR57_RS09360
HKClassicCurrent focus
1 962 485-1 963 894 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0209635Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1726898
Simplified PFAM architecture for HKOC_1726898
PFAM domain coverage: 302 / 469 aa (64.4%)
1 aa469 aa
GAF_PdtaSHisKA_2HATPase_c
- Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
- Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
- Domain count: 3
- Matched identifier: HKOC_1726898
- Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0209635
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002812585
AssemblyASM281258v1 · Complete Genomehaploid
Genome composition4 190 038 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key