Gene detail

DW153_RS12105

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_003473045

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003473045#DW153_RS12105Stable P2CS identifier used across views.
GenomeGCF_003473045Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1048754Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_182440389.1 · MIST4 DW153_RS12105RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage505 / 601 aa (84.0%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
dCache_1: 44-287 aa (244 aa)1HAMP: 306-375 aa (70 aa)2His_kinase: 390-469 aa (80 aa)3HATPase_c: 481-591 aa (111 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
44-287 aa · 244 aa · 40.6% of protein
Raw tokendCache_1:44:2.16e-19:287:248:195
2 HAMP#2
306-375 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:306:0.00000000000847:375:70:69
3 His_kinase#3
390-469 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:390:2.7e-36:469:80:80
4 HATPase_c#4
481-591 aa · 111 aa · 18.5% of protein
Raw tokenHATPase_c:481:6.84e-16:591:115:109
  • Raw architecture: dCache_1:44:2.16e-19:287:248:195#HAMP:306:0.00000000000847:375:70:69#His_kinase:390:2.7e-36:469:80:80#HATPase_c:481:6.84e-16:591:115:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003473045::NZ_QRLD01000016.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28123-31536Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW153_12100RefSeq proteinWP_182440389.1
Context group IDGCF_003473045::NZ_QRLD01000016.1::G00016
Context members
DW153_RS12100DW153_RS12105
Partner locus tags
DW153_RS12100DW153_RS12105
Partner old locus tags
DW153_12095DW153_12100
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_182440389.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW153_RS12105Primary locus identifier stored in the genes table.
Old locus tagDW153_12100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRLD01000016.1Sequence record reported by the local genomic context database.
Genomic interval29 731-31 536 nt1 806 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 123-31 536 ntGCF_003473045::NZ_QRLD01000016.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003473045::NZ_QRLD01000016.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRLD01000016.1All displayed genes belong to this local TCS context.
Neighborhood span28 123-31 536 nt3 414 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 123 nt31 536 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW153_RS12100GCF_003473045#DW153_RS12100
RRunclassified

28 123-29 727 nt · Forward (+)

Old locus DW153_12095RefSeq WP_101874907.1
DW153_RS12105GCF_003473045#DW153_RS12105
HKClassicCurrent focus

29 731-31 536 nt · Forward (+)

Old locus DW153_12100RefSeq WP_182440389.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1048754Run 6 · HK · 1 sequences
Representative sequenceGCF_003473045#DW153_RS12105The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HAMP + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1048754

Simplified PFAM architecture for HKOC_1048754

PFAM domain coverage: 484 / 601 aa (80.5%)

1 aa601 aa
dCache_1: 45-287 aadCache_1HAMP: 322-374 aaHAMPHis_kinase: 390-469 aaHis_kinaseHATPase_c: 484-591 aaHATPase_c
dCache_1HAMPHis_kinaseHATPase_c
  • Simplified architecture: dCache_1 + HAMP + His_kinase + HATPase_c
  • Raw architecture: dCache_1[45-287] | HAMP[322-374] | His_kinase[390-469] | HATPase_c[484-591]
  • Domain count: 4
  • Matched identifier: HKOC_1048754
  • Positioned domains: dCache_1 45-287 ; HAMP 322-374 ; His_kinase 390-469 ; HATPase_c 484-591
Cluster members and taxonomy
Visualization

Representative gene: GCF_003473045#DW153_RS12105

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_003473045
AssemblyASM347304v1 · Scaffoldhaploid
Genome composition3 323 923 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key