Gene detail

DW153_RS05670

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_003473045

ClassHKTypeClassicLength579 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003473045#DW153_RS05670Stable P2CS identifier used across views.
GenomeGCF_003473045Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1168407Run 6 · 14 sequences · id 100% · cov 80% · representative
External referencesWP_118315610.1 · A0AAJ1EUM1 · MIST4 DW153_RS05670RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length579 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage357 / 579 aa (61.7%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa579 aa
dCache_1: 173-267 aa (95 aa)1HAMP: 286-355 aa (70 aa)2His_kinase: 371-450 aa (80 aa)3HATPase_c: 466-577 aa (112 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
173-267 aa · 95 aa · 16.4% of protein
Raw tokendCache_1:173:0.0000277:267:114:195
2 HAMP#2
286-355 aa · 70 aa · 12.1% of protein
Raw tokenHAMP:286:0.0000000383:355:70:69
3 His_kinase#3
371-450 aa · 80 aa · 13.8% of protein
Raw tokenHis_kinase:371:2.72e-26:450:80:80
4 HATPase_c#4
466-577 aa · 112 aa · 19.3% of protein
Raw tokenHATPase_c:466:0.00000000018:577:112:109
  • Raw architecture: dCache_1:173:0.0000277:267:114:195#HAMP:286:0.0000000383:355:70:69#His_kinase:371:2.72e-26:450:80:80#HATPase_c:466:0.00000000018:577:112:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003473045::NZ_QRLD01000004.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span85659-89002Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW153_05670RefSeq proteinWP_118315610.1
Context group IDGCF_003473045::NZ_QRLD01000004.1::G00039
Context members
DW153_RS05670DW153_RS05675
Partner locus tags
DW153_RS05670DW153_RS05675
Partner old locus tags
DW153_05670DW153_05675
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_118315610.1Primary protein accession used for annex mappings.
UniProt accessionA0AAJ1EUM1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAJ1EUM1_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW153_RS05670Primary locus identifier stored in the genes table.
Old locus tagDW153_05670Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QRLD01000004.1Sequence record reported by the local genomic context database.
Genomic interval85 659-87 398 nt1 740 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span85 659-89 002 ntGCF_003473045::NZ_QRLD01000004.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003473045::NZ_QRLD01000004.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QRLD01000004.1All displayed genes belong to this local TCS context.
Neighborhood span85 659-89 002 nt3 344 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
85 659 nt89 002 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW153_RS05670GCF_003473045#DW153_RS05670
HKClassicCurrent focus

85 659-87 398 nt · Forward (+)

Old locus DW153_05670RefSeq WP_118315610.1
DW153_RS05675GCF_003473045#DW153_RS05675
RRunclassified

87 425-89 002 nt · Forward (+)

Old locus DW153_05675RefSeq WP_118315611.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1168407Run 6 · HK · 14 sequences
Representative sequenceGCF_003473045#DW153_RS05670The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1168407

Simplified PFAM architecture for HKOC_1168407

PFAM domain coverage: 190 / 579 aa (32.8%)

1 aa579 aa
His_kinase: 372-449 aaHis_kinaseHATPase_c: 466-577 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[372-449] | HATPase_c[466-577]
  • Domain count: 2
  • Matched identifier: HKOC_1168407
  • Positioned domains: His_kinase 372-449 ; HATPase_c 466-577
Cluster members and taxonomy
Visualization

Representative gene: GCF_003473045#DW153_RS05670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_003473045
AssemblyASM347304v1 · Scaffoldhaploid
Genome composition3 323 923 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 84 · HK 41 · RR 42CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key