Gene detail

DW746_RS04525

Histidine kinase, Classic

Blautia sp. AM28-36 · GCF_003462165

ClassHKTypeClassicLength583 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003462165#DW746_RS04525Stable P2CS identifier used across views.
GenomeGCF_003462165Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1148498Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_117760709.1 · MIST4 DW746_RS04525RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length583 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage190 / 583 aa (32.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa583 aa
His_kinase: 375-452 aa (78 aa)1HATPase_c: 472-583 aa (112 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
375-452 aa · 78 aa · 13.4% of protein
Raw tokenHis_kinase:375:1.08e-26:452:78:80
2 HATPase_c#2
472-583 aa · 112 aa · 19.2% of protein
Raw tokenHATPase_c:472:0.000000899:583:115:109
  • Raw architecture: His_kinase:375:1.08e-26:452:78:80#HATPase_c:472:0.000000899:583:115:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003462165::NZ_QTYM01000002.1::G00028
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span177175-178926Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW746_04540RefSeq proteinWP_117760709.1
Context group IDGCF_003462165::NZ_QTYM01000002.1::G00028
Context members
DW746_RS04525
Partner locus tags
DW746_RS04525
Partner old locus tags
DW746_04540
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_117760709.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW746_RS04525Primary locus identifier stored in the genes table.
Old locus tagDW746_04540Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTYM01000002.1Sequence record reported by the local genomic context database.
Genomic interval177 175-178 926 nt1 752 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span177 175-178 926 ntGCF_003462165::NZ_QTYM01000002.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003462165::NZ_QTYM01000002.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTYM01000002.1All displayed genes belong to this local TCS context.
Neighborhood span177 175-178 926 nt1 752 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
177 175 nt178 926 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

DW746_RS04525GCF_003462165#DW746_RS04525
HKClassicCurrent focus

177 175-178 926 nt · Forward (+)

Old locus DW746_04540RefSeq WP_117760709.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1148498Run 6 · HK · 4 sequences
Representative sequenceGCF_003462165#DW746_RS04525The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1148498

Simplified PFAM architecture for HKOC_1148498

PFAM domain coverage: 188 / 583 aa (32.2%)

1 aa583 aa
His_kinase: 375-453 aaHis_kinaseHATPase_c: 474-582 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[375-453] | HATPase_c[474-582]
  • Domain count: 2
  • Matched identifier: HKOC_1148498
  • Positioned domains: His_kinase 375-453 ; HATPase_c 474-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_003462165#DW746_RS04525

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 292 974 · GCF_003462165
AssemblyASM346216v1 · Scaffoldhaploid
Genome composition3 801 735 bp · 47,0% GCBlautia sp. AM28-36
Signal transduction countsGenes 102 · HK 51 · RR 49CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key