Gene detail

DW125_RS09995

Histidine kinase, Classic

Dorea sp. AM10-31 · GCF_003435815

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003435815#DW125_RS09995Stable P2CS identifier used across views.
GenomeGCF_003435815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1106393Run 6 · 5 sequences · id 100% · cov 80% · representative
External referencesWP_117538087.1 · A0ABR7F041 · MIST4 DW125_RS09995RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1His_kinaseHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage339 / 591 aa (57.4%)Merged over positioned domains only.
Domain description1 dCache_1,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
dCache_1: 112-262 aa (151 aa)1His_kinase: 362-441 aa (80 aa)2HATPase_c: 457-564 aa (108 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
112-262 aa · 151 aa · 25.5% of protein
Raw tokendCache_1:112:0.0000000000215:262:155:195
2 His_kinase#2
362-441 aa · 80 aa · 13.5% of protein
Raw tokenHis_kinase:362:5.02e-33:441:80:80
3 HATPase_c#3
457-564 aa · 108 aa · 18.3% of protein
Raw tokenHATPase_c:457:2.15e-16:564:111:109
  • Raw architecture: dCache_1:112:0.0000000000215:262:155:195#His_kinase:362:5.02e-33:441:80:80#HATPase_c:457:2.15e-16:564:111:109
  • Domain description: 1 dCache_1,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003435815::NZ_QTUV01000006.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span73867-77331Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW125_09990RefSeq proteinWP_117538087.1
Context group IDGCF_003435815::NZ_QTUV01000006.1::G00032
Context members
DW125_RS09990DW125_RS09995
Partner locus tags
DW125_RS09990DW125_RS09995
Partner old locus tags
DW125_09985DW125_09990
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_117538087.1Primary protein accession used for annex mappings.
UniProt accessionA0ABR7F041Primary UniProt accession resolved in the annex database.
UniProt IDA0ABR7F041_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW125_RS09995Primary locus identifier stored in the genes table.
Old locus tagDW125_09990Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTUV01000006.1Sequence record reported by the local genomic context database.
Genomic interval75 556-77 331 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span73 867-77 331 ntGCF_003435815::NZ_QTUV01000006.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435815::NZ_QTUV01000006.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTUV01000006.1All displayed genes belong to this local TCS context.
Neighborhood span73 867-77 331 nt3 465 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
73 867 nt77 331 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DW125_RS09990GCF_003435815#DW125_RS09990
RRunclassified

73 867-75 468 nt · Forward (+)

Old locus DW125_09985RefSeq WP_117538043.1
DW125_RS09995GCF_003435815#DW125_RS09995
HKClassicCurrent focus

75 556-77 331 nt · Forward (+)

Old locus DW125_09990RefSeq WP_117538087.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1106393Run 6 · HK · 5 sequences
Representative sequenceGCF_003435815#DW125_RS09995The current gene is the representative for this cluster.
PFAM architecturedCache_1 + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1106393

Simplified PFAM architecture for HKOC_1106393

PFAM domain coverage: 415 / 591 aa (70.2%)

1 aa591 aa
dCache_1: 34-261 aadCache_1His_kinase: 362-441 aaHis_kinaseHATPase_c: 458-564 aaHATPase_c
dCache_1His_kinaseHATPase_c
  • Simplified architecture: dCache_1 + His_kinase + HATPase_c
  • Raw architecture: dCache_1[34-261] | His_kinase[362-441] | HATPase_c[458-564]
  • Domain count: 3
  • Matched identifier: HKOC_1106393
  • Positioned domains: dCache_1 34-261 ; His_kinase 362-441 ; HATPase_c 458-564
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435815#DW125_RS09995

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 098 · GCF_003435815
AssemblyASM343581v1 · Scaffoldhaploid
Genome composition2 920 802 bp · 41,0% GCDorea sp. AM10-31
Signal transduction countsGenes 62 · HK 32 · RR 29CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key