Gene detail

DW125_RS00640

Histidine kinase, Hybrid

Dorea sp. AM10-31 · GCF_003435815

ClassHKTypeHybridLength1051 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003435815#DW125_RS00640Stable P2CS identifier used across views.
GenomeGCF_003435815Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_0258577Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_242992873.1 · MIST4 DW125_RS00640RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PilJGGDEFHisKAHATPase_cResponse_reg
Protein length1051 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage538 / 1051 aa (51.2%)Merged over positioned domains only.
Domain description1 PilJ,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for DW125_RS00640
Domain-by-domain annotation5 items
1 PilJ#1
37-123 aa · 87 aa · 8.3% of protein
Raw tokenPilJ:37:0.0000155:123:98:112
2 GGDEF#2
202-351 aa · 150 aa · 14.3% of protein
Raw tokenGGDEF:202:9.39e-23:351:157:160
3 HisKA#3
676-742 aa · 67 aa · 6.4% of protein
Raw tokenHisKA:676:0.000000000000665:742:67:64
4 HATPase_c#4
789-906 aa · 118 aa · 11.2% of protein
Raw tokenHATPase_c:789:2.83e-24:906:118:109
5 Response_reg#5
931-1046 aa · 116 aa · 11.0% of protein
Raw tokenResponse_reg:931:2.39e-28:1046:116:111
  • Raw architecture: PilJ:37:0.0000155:123:98:112#GGDEF:202:9.39e-23:351:157:160#HisKA:676:0.000000000000665:742:67:64#HATPase_c:789:2.83e-24:906:118:109#Response_reg:931:2.39e-28:1046:116:111
  • Domain description: 1 PilJ,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003435815::NZ_QTUV01000001.1::G00002
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span135548-138703Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDW125_00640RefSeq proteinWP_242992873.1
Context group IDGCF_003435815::NZ_QTUV01000001.1::G00002
Context members
DW125_RS00640
Partner locus tags
DW125_RS00640
Partner old locus tags
DW125_00640
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_242992873.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDW125_RS00640Primary locus identifier stored in the genes table.
Old locus tagDW125_00640Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QTUV01000001.1Sequence record reported by the local genomic context database.
Genomic interval135 548-138 703 nt3 156 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span135 548-138 703 ntGCF_003435815::NZ_QTUV01000001.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003435815::NZ_QTUV01000001.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QTUV01000001.1All displayed genes belong to this local TCS context.
Neighborhood span135 548-138 703 nt3 156 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
135 548 nt138 703 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

DW125_RS00640GCF_003435815#DW125_RS00640
HKHybridCurrent focus

135 548-138 703 nt · Reverse (-)

Old locus DW125_00640RefSeq WP_242992873.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0258577Run 6 · HK · 1 sequences
Representative sequenceGCF_003435815#DW125_RS00640The current gene is the representative for this cluster.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0258577

Simplified PFAM architecture for HKOC_0258577

PFAM domain coverage: 448 / 1051 aa (42.6%)

1 aa1051 aa
GGDEF: 202-352 aaGGDEFHisKA: 676-742 aaHisKAHATPase_c: 790-906 aaHATPase_cResponse_reg: 931-1043 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[202-352] | HisKA[676-742] | HATPase_c[790-906] | Response_reg[931-1043]
  • Domain count: 4
  • Matched identifier: HKOC_0258577
  • Positioned domains: GGDEF 202-352 ; HisKA 676-742 ; HATPase_c 790-906 ; Response_reg 931-1043
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435815#DW125_RS00640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 293 098 · GCF_003435815
AssemblyASM343581v1 · Scaffoldhaploid
Genome composition2 920 802 bp · 41,0% GCDorea sp. AM10-31
Signal transduction countsGenes 62 · HK 32 · RR 29CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key