1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw token
HisKA:117:0.000000000114:177:61:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DVB06_RS10085
Histidine kinase, Classic
Clostridioides difficile · GCF_003327025
ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003327025#DVB06_RS10085Stable P2CS identifier used across views.
GenomeGCF_003327025Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw token
HATPase_c:222:1.84e-24:328:108:109- Raw architecture: HisKA:117:0.000000000114:177:61:64#HATPase_c:222:1.84e-24:328:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003327025::NZ_QNWS01000008.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span37351-39013Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_003327025::NZ_QNWS01000008.1::G00029Context members
DVB06_RS10085DVB06_RS10090
Partner locus tags
DVB06_RS10085DVB06_RS10090
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003426036.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q7T1B8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q7T1B8_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDVB06_RS10085Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_QNWS01000008.1Sequence record reported by the local genomic context database.
Genomic interval37 351-38 340 nt990 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span37 351-39 013 ntGCF_003327025::NZ_QNWS01000008.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003327025::NZ_QNWS01000008.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QNWS01000008.1All displayed genes belong to this local TCS context.
Neighborhood span37 351-39 013 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
37 351 nt39 013 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DVB06_RS10085GCF_003327025#DVB06_RS10085
HKClassicCurrent focus
37 351-38 340 nt · Reverse (-)
DVB06_RS10090GCF_003327025#DVB06_RS10090
RROmpR
38 327-39 013 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_009903385#DDA10_RS21640Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1284413
Simplified PFAM architecture for HKOC_1284413
PFAM domain coverage: 357 / 553 aa (64.6%)
1 aa553 aa
Response_regTrans_reg_CHisKAHATPase_c
- Simplified architecture: Response_reg + Trans_reg_C + HisKA + HATPase_c
- Raw architecture: Response_reg[4-113] | Trans_reg_C[144-221] | HisKA[340-401] | HATPase_c[446-552]
- Domain count: 4
- Matched identifier: HKOC_1284413
- Positioned domains: Response_reg 4-113 ; Trans_reg_C 144-221 ; HisKA 340-401 ; HATPase_c 446-552
Cluster members and taxonomy
Representative gene: GCF_009903385#DDA10_RS21640
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003327025
AssemblyASM332702v1 · Scaffoldhaploid
Genome composition4 210 800 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key