Gene detail

CDIF27640_RS09365

Histidine kinase, Classic

Clostridioides difficile · GCF_003313585

ClassHKTypeClassicLength664 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003313585#CDIF27640_RS09365Stable P2CS identifier used across views.
GenomeGCF_003313585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0860209Run 6 · 349 sequences · id 100% · cov 80%
External referencesWP_009889695.1 · A0A0H3N2M2 · MIST4 CDIF27640_RS09365RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

SBP_bac_3HisKAHATPase_c
Protein length664 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage386 / 664 aa (58.1%)Merged over positioned domains only.
Domain description1 SBP_bac_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDIF27640_RS09365
Domain-by-domain annotation3 items
1 SBP_bac_3#1
58-278 aa · 221 aa · 33.3% of protein
Raw tokenSBP_bac_3:58:1.72e-41:278:230:224
2 HisKA#2
446-508 aa · 63 aa · 9.5% of protein
Raw tokenHisKA:446:0.0000000000000409:508:63:64
3 HATPase_c#3
557-658 aa · 102 aa · 15.4% of protein
Raw tokenHATPase_c:557:2.12e-23:658:103:109
  • Raw architecture: SBP_bac_3:58:1.72e-41:278:230:224#HisKA:446:0.0000000000000409:508:63:64#HATPase_c:557:2.12e-23:658:103:109
  • Domain description: 1 SBP_bac_3,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003313585::NZ_CP011848.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1930516-1933832Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF27640_01852RefSeq proteinWP_009889695.1
Context group IDGCF_003313585::NZ_CP011848.1::G00029
Context members
CDIF27640_RS09365CDIF27640_RS09370
Partner locus tags
CDIF27640_RS09365CDIF27640_RS09370
Partner old locus tags
CDIF27640_01852CDIF27640_01853
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889695.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2M2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2M2_CLODCDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDIF27640_RS09365Primary locus identifier stored in the genes table.
Old locus tagCDIF27640_01852Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP011848.1Sequence record reported by the local genomic context database.
Genomic interval1 930 516-1 932 510 nt1 995 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 930 516-1 933 832 ntGCF_003313585::NZ_CP011848.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003313585::NZ_CP011848.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP011848.1All displayed genes belong to this local TCS context.
Neighborhood span1 930 516-1 933 832 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 930 516 nt1 933 832 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDIF27640_RS09365GCF_003313585#CDIF27640_RS09365
HKClassicCurrent focus

1 930 516-1 932 510 nt · Forward (+)

Old locus CDIF27640_01852RefSeq WP_009889695.1
CDIF27640_RS09370GCF_003313585#CDIF27640_RS09370
RRNtrC

1 932 510-1 933 832 nt · Forward (+)

Old locus CDIF27640_01853RefSeq WP_009893260.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0860209Run 6 · HK · 349 sequences
Representative sequenceGCF_000003215#QAC_RS0208985Use this link to inspect the representative gene detail.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0860209

Simplified PFAM architecture for HKOC_0860209

PFAM domain coverage: 385 / 664 aa (58.0%)

1 aa664 aa
SBP_bac_3: 60-277 aaSBP_bac_3HisKA: 448-509 aaHisKAHATPase_c: 555-659 aaHATPase_c
SBP_bac_3HisKAHATPase_c
  • Simplified architecture: SBP_bac_3 + HisKA + HATPase_c
  • Raw architecture: SBP_bac_3[60-277] | HisKA[448-509] | HATPase_c[555-659]
  • Domain count: 3
  • Matched identifier: HKOC_0860209
  • Positioned domains: SBP_bac_3 60-277 ; HisKA 448-509 ; HATPase_c 555-659
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0208985

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003313585
AssemblyASM331358v1 · Complete Genomehaploid
Genome composition4 229 629 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key