1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw token
HisKA:89:0.0000000554:151:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDIF27640_RS02265
Histidine kinase, Classic
Clostridioides difficile · GCF_003313585
ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003313585#CDIF27640_RS02265Stable P2CS identifier used across views.
GenomeGCF_003313585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw token
HATPase_c:199:8.88e-30:306:108:109- Raw architecture: HisKA:89:0.0000000554:151:63:64#HATPase_c:199:8.88e-30:306:108:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003313585::NZ_CP011848.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span401013-402639Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCDIF27640_00458RefSeq proteinWP_009888178.1
Context group ID
GCF_003313585::NZ_CP011848.1::G00002Context members
CDIF27640_RS02265CDIF27640_RS02270
Partner locus tags
CDIF27640_RS02265CDIF27640_RS02270
Partner old locus tags
CDIF27640_00458CDIF27640_00459
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009888178.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MYW5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MYW5_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDIF27640_RS02265Primary locus identifier stored in the genes table.
Old locus tagCDIF27640_00458Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP011848.1Sequence record reported by the local genomic context database.
Genomic interval401 013-401 936 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span401 013-402 639 ntGCF_003313585::NZ_CP011848.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003313585::NZ_CP011848.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP011848.1All displayed genes belong to this local TCS context.
Neighborhood span401 013-402 639 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
401 013 nt402 639 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDIF27640_RS02265GCF_003313585#CDIF27640_RS02265
HKClassicCurrent focus
401 013-401 936 nt · Reverse (-)
CDIF27640_RS02270GCF_003313585#CDIF27640_RS02270
RROmpR
401 938-402 639 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202000Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2880535
Simplified PFAM architecture for HKOC_2880535
PFAM domain coverage: 172 / 307 aa (56.0%)
1 aa307 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[88-151] | HATPase_c[199-306]
- Domain count: 2
- Matched identifier: HKOC_2880535
- Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202000
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003313585
AssemblyASM331358v1 · Complete Genomehaploid
Genome composition4 229 629 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key