Gene detail

C4N21_RS12465

Histidine kinase, Classic

Faecalibacterium prausnitzii · GCF_003287475

ClassHKTypeClassicLength605 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003287475#C4N21_RS12465Stable P2CS identifier used across views.
GenomeGCF_003287475Bacteria; Bacillati; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae; Faecalibacterium
Selected clusterHKOC_1029344Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_112121950.1 · A0A329UQV6 · MIST4 C4N21_RS12465RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length605 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 605 aa (43.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa605 aa
HAMP: 295-365 aa (71 aa)1His_kinase: 382-461 aa (80 aa)2HATPase_c: 484-593 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
295-365 aa · 71 aa · 11.7% of protein
Raw tokenHAMP:295:0.0000000665:365:72:69
2 His_kinase#2
382-461 aa · 80 aa · 13.2% of protein
Raw tokenHis_kinase:382:2.06e-29:461:80:80
3 HATPase_c#3
484-593 aa · 110 aa · 18.2% of protein
Raw tokenHATPase_c:484:0.0000000000000078:593:110:109
  • Raw architecture: HAMP:295:0.0000000665:365:72:69#His_kinase:382:2.06e-29:461:80:80#HATPase_c:484:0.0000000000000078:593:110:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003287475::NZ_PRLF01000023.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8420-11474Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4N21_12455RefSeq proteinWP_112121950.1
Context group IDGCF_003287475::NZ_PRLF01000023.1::G00016
Context members
C4N21_RS12460C4N21_RS12465
Partner locus tags
C4N21_RS12460C4N21_RS12465
Partner old locus tags
C4N21_12450C4N21_12455
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_112121950.1Primary protein accession used for annex mappings.
UniProt accessionA0A329UQV6Primary UniProt accession resolved in the annex database.
UniProt IDA0A329UQV6_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC4N21_RS12465Primary locus identifier stored in the genes table.
Old locus tagC4N21_12455Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PRLF01000023.1Sequence record reported by the local genomic context database.
Genomic interval9 657-11 474 nt1 818 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span8 420-11 474 ntGCF_003287475::NZ_PRLF01000023.1::G00016

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003287475::NZ_PRLF01000023.1::G00016

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PRLF01000023.1All displayed genes belong to this local TCS context.
Neighborhood span8 420-11 474 nt3 055 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 420 nt11 474 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C4N21_RS12460GCF_003287475#C4N21_RS12460
RRunclassified

8 420-9 682 nt · Reverse (-)

Old locus C4N21_12450RefSeq WP_112121949.1
C4N21_RS12465GCF_003287475#C4N21_RS12465
HKClassicCurrent focus

9 657-11 474 nt · Reverse (-)

Old locus C4N21_12455RefSeq WP_112121950.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1029344Run 6 · HK · 1 sequences
Representative sequenceGCF_003287475#C4N21_RS12465The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1029344

Simplified PFAM architecture for HKOC_1029344

PFAM domain coverage: 237 / 605 aa (39.2%)

1 aa605 aa
HAMP: 316-365 aaHAMPHis_kinase: 383-460 aaHis_kinaseHATPase_c: 484-592 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[316-365] | His_kinase[383-460] | HATPase_c[484-592]
  • Domain count: 3
  • Matched identifier: HKOC_1029344
  • Positioned domains: HAMP 316-365 ; His_kinase 383-460 ; HATPase_c 484-592
Cluster members and taxonomy
Visualization

Representative gene: GCF_003287475#C4N21_RS12465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 853 · GCF_003287475
AssemblyASM328747v1 · Contighaploid
Genome composition3 018 140 bp · 56,5% GCFaecalibacterium prausnitzii
Signal transduction countsGenes 50 · HK 22 · RR 26CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderEubacterialesFamilyOscillospiraceaeGenusFaecalibacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Eubacteriales6Oscillospiraceae7Faecalibacterium

Related genes

Preview from the same derived genome key