Gene detail

DDG61_RS19275

Histidine kinase, Classic

Clostridioides difficile · GCF_003095695

ClassHKTypeClassicLength329 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003095695#DDG61_RS19275Stable P2CS identifier used across views.
GenomeGCF_003095695Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1284413Run 6 · 434 sequences · id 100% · cov 80%
External referencesWP_003426036.1 · A0A9Q7T1B8 · MIST4 DDG61_RS19275RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length329 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 329 aa (51.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa329 aa
HisKA: 117-177 aa (61 aa)1HATPase_c: 222-328 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
117-177 aa · 61 aa · 18.5% of protein
Raw tokenHisKA:117:0.000000000114:177:61:64
2 HATPase_c#2
222-328 aa · 107 aa · 32.5% of protein
Raw tokenHATPase_c:222:1.84e-24:328:108:109
  • Raw architecture: HisKA:117:0.000000000114:177:61:64#HATPase_c:222:1.84e-24:328:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003095695::NZ_CP029152.1::G00055
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4132806-4134468Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDDG61_19275RefSeq proteinWP_003426036.1
Context group IDGCF_003095695::NZ_CP029152.1::G00055
Context members
DDG61_RS19275DDG61_RS19280
Partner locus tags
DDG61_RS19275DDG61_RS19280
Partner old locus tags
DDG61_19275DDG61_19280
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003426036.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q7T1B8Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q7T1B8_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDDG61_RS19275Primary locus identifier stored in the genes table.
Old locus tagDDG61_19275Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP029152.1Sequence record reported by the local genomic context database.
Genomic interval4 132 806-4 133 795 nt990 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 132 806-4 134 468 ntGCF_003095695::NZ_CP029152.1::G00055

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003095695::NZ_CP029152.1::G00055

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP029152.1All displayed genes belong to this local TCS context.
Neighborhood span4 132 806-4 134 468 nt1 663 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 132 806 nt4 134 468 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DDG61_RS19275GCF_003095695#DDG61_RS19275
HKClassicCurrent focus

4 132 806-4 133 795 nt · Reverse (-)

Old locus DDG61_19275RefSeq WP_003426036.1
DDG61_RS19280GCF_003095695#DDG61_RS19280
RROmpR

4 133 782-4 134 468 nt · Reverse (-)

Old locus DDG61_19280RefSeq WP_003426037.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1284413Run 6 · HK · 434 sequences
Representative sequenceGCF_009903385#DDA10_RS21640Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1284413

Simplified PFAM architecture for HKOC_1284413

PFAM domain coverage: 357 / 553 aa (64.6%)

1 aa553 aa
Response_reg: 4-113 aaResponse_regTrans_reg_C: 144-221 aaTrans_reg_CHisKA: 340-401 aaHisKAHATPase_c: 446-552 aaHATPase_c
Response_regTrans_reg_CHisKAHATPase_c
  • Simplified architecture: Response_reg + Trans_reg_C + HisKA + HATPase_c
  • Raw architecture: Response_reg[4-113] | Trans_reg_C[144-221] | HisKA[340-401] | HATPase_c[446-552]
  • Domain count: 4
  • Matched identifier: HKOC_1284413
  • Positioned domains: Response_reg 4-113 ; Trans_reg_C 144-221 ; HisKA 340-401 ; HATPase_c 446-552
Cluster members and taxonomy
Visualization

Representative gene: GCF_009903385#DDA10_RS21640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003095695
AssemblyASM309569v1 · Complete Genomehaploid
Genome composition4 289 548 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key