Gene detail

C3350_RS07590

Histidine kinase, Classic

Clostridioides difficile · GCF_002945855

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_002945855#C3350_RS07590Stable P2CS identifier used across views.
GenomeGCF_002945855Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293402Run 6 · 360 sequences · id 100% · cov 80%
External referencesWP_012816133.1 · A0A0H3N1Q8 · MIST4 C3350_RS07590RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for C3350_RS07590
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.000000000946:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:1.63e-21:410:107:109
  • Raw architecture: HisKA:199:0.000000000946:258:60:64#HATPase_c:304:1.63e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_002945855::NZ_CP026595.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1565019-1566954Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC3350_07590RefSeq proteinWP_012816133.1
Context group IDGCF_002945855::NZ_CP026595.1::G00022
Context members
C3350_RS07585C3350_RS07590
Partner locus tags
C3350_RS07585C3350_RS07590
Partner old locus tags
C3350_07585C3350_07590
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816133.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1Q8Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1Q8_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagC3350_RS07590Primary locus identifier stored in the genes table.
Old locus tagC3350_07590Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP026595.1Sequence record reported by the local genomic context database.
Genomic interval1 565 701-1 566 954 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 565 019-1 566 954 ntGCF_002945855::NZ_CP026595.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_002945855::NZ_CP026595.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP026595.1All displayed genes belong to this local TCS context.
Neighborhood span1 565 019-1 566 954 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 565 019 nt1 566 954 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

C3350_RS07585GCF_002945855#C3350_RS07585
RROmpR

1 565 019-1 565 723 nt · Forward (+)

Old locus C3350_07585RefSeq WP_009899785.1
C3350_RS07590GCF_002945855#C3350_RS07590
HKClassicCurrent focus

1 565 701-1 566 954 nt · Forward (+)

Old locus C3350_07590RefSeq WP_012816133.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293402Run 6 · HK · 360 sequences
Representative sequenceGCF_000003215#QAC_RS0207205Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293402

Simplified PFAM architecture for HKOC_2293402

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293402
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0207205

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 360 total members. Page 1 / 8.

GCF_000003215#QAC_RS0207205 (representative)
QAC_RS0207205 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000027105#CDR20291_RS07185
CDR20291_RS07185 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000085225#CD196_RS07345
CD196_RS07345 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000154645#UAA_RS0209075
UAA_RS0209075 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000154665#QAD_RS0207390
QAD_RS0207390 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000154685#AEC_RS0208675
AEC_RS0208675 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000155045#EAA_RS0207110
EAA_RS0207110 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000210455#CD7855_RS07175
CD7855_RS07175 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000211235#CDBI1_RS07270
CDBI1_RS07270 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000450765#QO5_RS07975
QO5_RS07975 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000451065#QSC_RS07015
QSC_RS07015 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000451785#QSO_RS06010
QSO_RS06010 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000451885#QU5_RS07065
QU5_RS07065 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000452005#QUI_RS11300
QUI_RS11300 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_000826625#BN2378_RS15805
BN2378_RS15805 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_001484885#CD26A54R_RS07160
CD26A54R_RS07160 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_001484895#CD26A54S_RS07240
CD26A54S_RS07240 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_001857645#HMPREF3082_RS06165
HMPREF3082_RS06165 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_001971835#BER28_RS07570
BER28_RS07570 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_001972015#BER29_RS07515
BER29_RS07515 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002301165#BGU11_RS13535
BGU11_RS13535 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002301255#BGU15_RS02295
BGU15_RS02295 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002302755#BGV00_RS08950
BGV00_RS08950 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002303105#BGV21_RS16370
BGV21_RS16370 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002335485#NCKUH21_RS06970
NCKUH21_RS06970 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002812585#CWR57_RS06900
CWR57_RS06900 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002891615#AMR88_RS07840
AMR88_RS07840 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945415#C3W74_RS07575
C3W74_RS07575 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945515#C3L34_RS07560
C3L34_RS07560 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945665#C3347_RS07580
C3347_RS07580 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945755#C3348_RS07580
C3348_RS07580 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945855#C3350_RS07590
C3350_RS07590 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002945945#C3349_RS07580
C3349_RS07580 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002946135#C3352_RS07590
C3352_RS07590 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002946195#C3353_RS07580
C3353_RS07580 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_002954285#AMR92_RS03150
AMR92_RS03150 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003313545#CDIF27638_RS07570
CDIF27638_RS07570 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003313585#CDIF27640_RS07560
CDIF27640_RS07560 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003482035#CDIF28196_RS07575
CDIF28196_RS07575 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003597795#DA426_RS12345
DA426_RS12345 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003597815#DA430_RS07565
DA430_RS07565 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003597835#DA432_RS07520
DA432_RS07520 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003597895#DA422_RS07465
DA422_RS07465 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003597915#DA436_RS07515
DA436_RS07515 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003625415#C0215_RS05345
C0215_RS05345 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003625425#C0983_RS00035
C0983_RS00035 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003625435#C0984_RS04980
C0984_RS04980 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003862685#EGM06_RS06060
EGM06_RS06060 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8
GCF_003862945#EGL88_RS13650
EGL88_RS13650 · HK · Classic
RefSeq: WP_074104059.1
GCF_003863035#EGL82_RS08180
EGL82_RS08180 · HK · Classic
RefSeq: WP_012816133.1
UniProt: A0A0H3N1Q8

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_002945855
AssemblyASM294585v1 · Complete Genomehaploid
Genome composition4 119 932 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key