Gene detail

AEC_RS0208675

Histidine kinase, Classic

Clostridioides difficile QCD-37x79 · GCF_000154685

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000154685#AEC_RS0208675Stable P2CS identifier used across views.
GenomeGCF_000154685Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293402Run 6 · 360 sequences · id 100% · cov 80%
External referencesWP_012816133.1 · A0A0H3N1Q8 · MIST4 AEC_RS0208675RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for AEC_RS0208675
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.000000000946:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:1.63e-21:410:107:109
  • Raw architecture: HisKA:199:0.000000000946:258:60:64#HATPase_c:304:1.63e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000154685::NZ_CM000658.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1503313-1505269Genomic interval covered by the local TCS group.
Context group IDGCF_000154685::NZ_CM000658.1::G00022
Context members
AEC_RS0208670AEC_RS0208675
Partner locus tags
AEC_RS0208670AEC_RS0208675
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816133.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1Q8Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1Q8_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagAEC_RS0208675Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CM000658.1Sequence record reported by the local genomic context database.
Genomic interval1 504 016-1 505 269 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 503 313-1 505 269 ntGCF_000154685::NZ_CM000658.1::G00022

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000154685::NZ_CM000658.1::G00022

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CM000658.1All displayed genes belong to this local TCS context.
Neighborhood span1 503 313-1 505 269 nt1 957 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 503 313 nt1 505 269 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

AEC_RS0208670GCF_000154685#AEC_RS0208670
RROmpR

1 503 313-1 504 038 nt · Forward (+)

RefSeq WP_009889278.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293402Run 6 · HK · 360 sequences
Representative sequenceGCF_000003215#QAC_RS0207205Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293402

Simplified PFAM architecture for HKOC_2293402

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293402
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0207205

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 479 834 · GCF_000154685
Assemblycdqaf · Chromosomehaploid
Genome composition4 332 988 bp · 28,5% GCClostridioides difficile QCD-37x79
Signal transduction countsGenes 107 · HK 50 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key