1 PAS_4#1
142-250 aa · 109 aa · 21.2% of protein
Raw token
PAS_4:142:0.000000000206:250:115:110P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AWI45_RS01090
Histidine kinase, Classic
Clostridioides difficile · GCF_002939365
ClassHKTypeClassicLength514 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_002939365#AWI45_RS01090Stable P2CS identifier used across views.
GenomeGCF_002939365Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_4HisKAHATPase_c
Protein length514 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 514 aa (56.4%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
259-328 aa · 70 aa · 13.6% of protein
Raw token
HisKA:259:0.00000000000000212:328:70:643 HATPase_c#3
375-485 aa · 111 aa · 21.6% of protein
Raw token
HATPase_c:375:9.84e-28:485:111:109- Raw architecture: PAS_4:142:0.000000000206:250:115:110#HisKA:259:0.00000000000000212:328:70:64#HATPase_c:375:9.84e-28:485:111:109
- Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_002939365::NZ_LQZJ01000022.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span60121-61665Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAWI45_11350RefSeq proteinWP_243675299.1
Context group ID
GCF_002939365::NZ_LQZJ01000022.1::G00003Context members
AWI45_RS01090
Partner locus tags
AWI45_RS01090
Partner old locus tags
AWI45_11350
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_243675299.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAWI45_RS01090Primary locus identifier stored in the genes table.
Old locus tagAWI45_11350Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_LQZJ01000022.1Sequence record reported by the local genomic context database.
Genomic interval60 121-61 665 nt1 545 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span60 121-61 665 ntGCF_002939365::NZ_LQZJ01000022.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_002939365::NZ_LQZJ01000022.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_LQZJ01000022.1All displayed genes belong to this local TCS context.
Neighborhood span60 121-61 665 nt1 545 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 121 nt61 665 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
AWI45_RS01090GCF_002939365#AWI45_RS01090
HKClassicCurrent focus
60 121-61 665 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_002939365#AWI45_RS01090The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1411990
Simplified PFAM architecture for HKOC_1411990
PFAM domain coverage: 290 / 514 aa (56.4%)
1 aa514 aa
PAS_4HisKAHATPase_c
- Simplified architecture: PAS_4 + HisKA + HATPase_c
- Raw architecture: PAS_4[142-250] | HisKA[259-328] | HATPase_c[375-485]
- Domain count: 3
- Matched identifier: HKOC_1411990
- Positioned domains: PAS_4 142-250 ; HisKA 259-328 ; HATPase_c 375-485
Cluster members and taxonomy
Representative gene: GCF_002939365#AWI45_RS01090
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_002939365
AssemblyASM293936v1 · Contighaploid
Genome composition4 160 193 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 91 · HK 43 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key